L-nucleosides containing modified nucleobases

Autor(en): Seela, F
Lin, W
Kazimierczuk, Z
Rosemeyer, H 
Glacon, V
Peng, X
He, Y
Ming, X
Andrzejewska, M
Gorska, A
Zhang, X
La Colla, P
Stichwörter: 7-deazapurine; 8-aza-7-deazapurine; antiviral activity; benzimidazole; Biochemistry & Molecular Biology; conformation; glycosylation; imidazo [1,2-a]-s-triazine; L-nucleosides; X-ray analysis
Erscheinungsdatum: 2005
Herausgeber: TAYLOR & FRANCIS INC
Journal: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volumen: 24
Ausgabe: 5-7, SI
Startseite: 859
Seitenende: 863
Zusammenfassung: 
The synthesis of base modified L-nucleosides is described with pyrrolo[2,3-d]pyrimidines, pyrazolo[3,4-d]pyrimidines, benzimidazoles, and imidazo[1,2-a]-s-triazines as nucleobases. The conformation of the nucleosides is studied and the antiviral activity is evaluated.
Beschreibung: 
16th International Roundtable of the International-Society-for-Nucleosides-Nucleotides-and-Nucleic-Acids (IS3NA), Univ Minnesota, Ctr Drug Design, Minneapolis, MN, SEP 12-16, 2004
ISSN: 15257770
DOI: 10.1081/NCN-200059206

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