L-nucleosides containing modified nucleobases
| Autor(en): | Seela, F Lin, W Kazimierczuk, Z Rosemeyer, H Glacon, V Peng, X He, Y Ming, X Andrzejewska, M Gorska, A Zhang, X La Colla, P |
Stichwörter: | 7-deazapurine; 8-aza-7-deazapurine; antiviral activity; benzimidazole; Biochemistry & Molecular Biology; conformation; glycosylation; imidazo [1,2-a]-s-triazine; L-nucleosides; X-ray analysis | Erscheinungsdatum: | 2005 | Herausgeber: | TAYLOR & FRANCIS INC | Journal: | NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | Volumen: | 24 | Ausgabe: | 5-7, SI | Startseite: | 859 | Seitenende: | 863 | Zusammenfassung: | The synthesis of base modified L-nucleosides is described with pyrrolo[2,3-d]pyrimidines, pyrazolo[3,4-d]pyrimidines, benzimidazoles, and imidazo[1,2-a]-s-triazines as nucleobases. The conformation of the nucleosides is studied and the antiviral activity is evaluated. |
Beschreibung: | 16th International Roundtable of the International-Society-for-Nucleosides-Nucleotides-and-Nucleic-Acids (IS3NA), Univ Minnesota, Ctr Drug Design, Minneapolis, MN, SEP 12-16, 2004 |
ISSN: | 15257770 | DOI: | 10.1081/NCN-200059206 |
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geprüft am 05.05.2024
