Ion-specific aggregation of gold-DNA nanoparticles using the dG quartet hairpin 5 `-d(G(4)T(4)G(4))

DC FieldValueLanguage
dc.contributor.authorSeela, F
dc.contributor.authorJawalekar, AM
dc.contributor.authorChi, LF
dc.contributor.authorZhong, DY
dc.date.accessioned2021-12-23T16:13:09Z-
dc.date.available2021-12-23T16:13:09Z-
dc.date.issued2005
dc.identifier.issn16121872
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/10433-
dc.description.abstractIon-selective self-assembly of An nanoparticles is described. The Oxytricha telomere DNA hairpin 5'-d(G(4)T(4)G(4)) immobilized on 13-nm Au nanoparticles forms a supramolecular assembly via dG-quartets, as determined by the color change and by scanning electron microscopy (SEM). The aggregation is ion-dependent and selective for Na+ ions. K+ is less efficient, while Li+ and Cs+ do not drive the aggregation. This work is the first effort to explore the use of secondary structures of DNA (quadruplexes) for producing self-assemblies of Au nanoparticles. It can be utilized to generate novel devices and materials, potentially useful for sensing and other applications in medicinal or engineering science.
dc.language.isoen
dc.publisherVERLAG HELVETICA CHIMICA ACTA AG
dc.relation.ispartofCHEMISTRY & BIODIVERSITY
dc.subjectBiochemistry & Molecular Biology
dc.subjectChemistry
dc.subjectChemistry, Multidisciplinary
dc.subjectG-QUADRUPLEX
dc.subjectPOLYNUCLEOTIDES
dc.subjectSTABILITY
dc.titleIon-specific aggregation of gold-DNA nanoparticles using the dG quartet hairpin 5 `-d(G(4)T(4)G(4))
dc.typejournal article
dc.identifier.doi10.1002/cbdv.200490168
dc.identifier.isiISI:000226963500005
dc.description.volume2
dc.description.issue1
dc.description.startpage84
dc.description.endpage91
dc.contributor.orcid0000-0001-5650-4767
dc.contributor.researcheridA-1419-2015
dc.contributor.researcheridD-5617-2017
dc.publisher.placeHOFWIESENSTRASSE 26, POSTFACH, CH-8042 ZURICH, SWITZERLAND
dcterms.isPartOf.abbreviationChem. Biodivers.
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