Homeostatic regulation upon changes of enzyme activities in the Calvin cycle as an example for general mechanisms of flux control. What can we expect from transgenic plants?

DC FieldValueLanguage
dc.contributor.authorFridlyand, LE
dc.contributor.authorBackhausen, JE
dc.contributor.authorScheibe, R
dc.date.accessioned2021-12-23T16:13:35Z-
dc.date.available2021-12-23T16:13:35Z-
dc.date.issued1999
dc.identifier.issn01668595
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/10646-
dc.description.abstractIn order to explain the mechanisms of Calvin-cycle regulation, the general properties of metabolic systems under homeostatic flux control are analyzed. It is shown that the main characteristic point for an enzyme in such a system can be the value of a sharp transition from some constant homeostatic flux to a limitation by this enzyme. A special method for the quantitative treatment of the experimental dependence of a metabolic flux such as photosynthesis on enzyme content is developed. It is pointed out that reactions close to a thermodynamic equilibrium under normal conditions can considerably limit the homeostatic fluxes with a decrease of the enzyme content. Calvin-cycle enzymes are classified as non-limiting, near-limiting and limiting. The deduced rules for the regulation of a homeostatic metabolic pathway are used to explain the data obtained for transgenic plants with reduced activities of Calvin-cycle enzymes. The role of compensating mechanisms that maintain the photosynthesis rate constant upon the changes of enzyme contents is analyzed for the Calvin cycle. The developed analysis explains the sharp transitions between limiting and non-limiting conditions that can be seen in transgenic plants with reduced content of some Calvin-cycle enzymes, and the limiting role of such reversible enzymes as aldolase, transketolase and others. The attempt is made to predict the properties of plants with increased enzyme contents in the Calvin cycle.
dc.language.isoen
dc.publisherSPRINGER
dc.relation.ispartofPHOTOSYNTHESIS RESEARCH
dc.subject3-PHOSPHOGLYCERATE REDUCTION
dc.subjectANTISENSE RNA
dc.subjectC-3 PLANTS
dc.subjectCO2 ASSIMILATION
dc.subjectGROWTH
dc.subjectmetabolic control analysis
dc.subjectPHOSPHORIBULOKINASE ACTIVITY
dc.subjectPHOTOSYNTHESIS
dc.subjectPlant Sciences
dc.subjectPOTATO PLANTS
dc.subjectRIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE-OXYGENASE
dc.subjectTOBACCO PLANTS
dc.titleHomeostatic regulation upon changes of enzyme activities in the Calvin cycle as an example for general mechanisms of flux control. What can we expect from transgenic plants?
dc.typejournal article
dc.identifier.doi10.1023/A:1006342812049
dc.identifier.isiISI:000084401700004
dc.description.volume61
dc.description.issue3
dc.description.startpage227
dc.description.endpage239
dc.contributor.orcid0000-0003-4424-9986
dc.identifier.eissn15735079
dc.publisher.placeVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
dcterms.isPartOf.abbreviationPhotosynth. Res.
crisitem.author.deptFB 05 - Biologie/Chemie-
crisitem.author.deptidfb05-
crisitem.author.orcid0000-0002-6140-6181-
crisitem.author.parentorgUniversität Osnabrück-
crisitem.author.netidScRe288-
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