Surface functionalisation of sol-gel derived aluminosilicates in simulated body fluids

Abstract

Iron containing aluminosilicate systems obtained by sol-gel method are investigated as potential biomaterials for hyperthermia. The samples surface functionalisation in simulated body fluid enriched with bovine serum albumin (BSA) was studied by Fourier-transform infrared spectroscopy performed in reflectance mode and X-ray photoelectron spectroscopy (XPS). beta-sheet/turns ratio estimated using the deconvolution of IR absorption band corresponding to amide I of adsorbed BSA on surface samples indicates a positive contribution to the biocompatibility of these materials. XPS results show an early attachment of albumin on sample surface that is weakly influenced by the protein concentration and prolonged immersion time in BSA-SBF solution. (c) 2009 Elsevier B.V. All rights reserved.