DC Element | Wert | Sprache |
dc.contributor.author | NONA, SN | |
dc.contributor.author | DUNCAN, A | |
dc.contributor.author | STAFFORD, CA | |
dc.contributor.author | MAGGS, A | |
dc.contributor.author | JESERICH, G | |
dc.contributor.author | CRONLYDILLON, JR | |
dc.date.accessioned | 2021-12-23T16:18:38Z | - |
dc.date.available | 2021-12-23T16:18:38Z | - |
dc.date.issued | 1992 | |
dc.identifier.issn | 03004864 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/12776 | - |
dc.description.abstract | This study uses immunohistochemistry and EM to examine the site of injury in goldfish optic nerve during axonal regeneration. Within seven days of nerve crush axons begin to regrow and a network of GFAP+ reactive astrocytes appears in the nerve on either side of the injury. However, the damaged area remains GFAP-. By42 days after nerve crush, the sheaths of new axons acquire myelin marker 6D2, and the crush area becomes populated by a mass of longitudinally-orientated S-100+ cells. Ultrastructurally, the predominant cells in the crush area bear a strong resemblance to peripheral nerve Schwann cells; they display a one-to-one association with myelinated axons, have a basal lamina and are surrounded by collagen fibres. It is proposed that these cells are Schwann cells which enter the optic nerve as a result of crush, where they become confined to the astrocyte-free crush area. | |
dc.language.iso | en | |
dc.publisher | CHAPMAN HALL LTD | |
dc.relation.ispartof | JOURNAL OF NEUROCYTOLOGY | |
dc.subject | ACIDIC PROTEIN GFAP | |
dc.subject | ADULT-RATS | |
dc.subject | Cell Biology | |
dc.subject | EXPRESSION | |
dc.subject | GANGLION | |
dc.subject | IMMUNOHISTOCHEMICAL LOCALIZATION | |
dc.subject | INJURY | |
dc.subject | Neurosciences | |
dc.subject | Neurosciences & Neurology | |
dc.subject | REMYELINATION | |
dc.subject | SPINAL-CORD | |
dc.subject | SYSTEM | |
dc.subject | TROUT | |
dc.title | MYELINATION OF REGENERATED AXONS IN GOLDFISH OPTIC-NERVE BY SCHWANN-CELLS | |
dc.type | journal article | |
dc.identifier.doi | 10.1007/BF01191504 | |
dc.identifier.isi | ISI:A1992HY56900001 | |
dc.description.volume | 21 | |
dc.description.issue | 6 | |
dc.description.startpage | 391 | |
dc.description.endpage | 401 | |
dc.publisher.place | 2-6 BOUNDARY ROW, LONDON, ENGLAND SE1 8HN | |
dcterms.isPartOf.abbreviation | J. Neurocytol. | |