Laser therapies for onychomycosis - critical evaluation of methods and effectiveness

DC FieldValueLanguage
dc.contributor.authorFrancuzik, W.
dc.contributor.authorFritz, K.
dc.contributor.authorSalavastru, C.
dc.date.accessioned2021-12-23T16:21:02Z-
dc.date.available2021-12-23T16:21:02Z-
dc.date.issued2016
dc.identifier.issn09269959
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/13698-
dc.description.abstractThe number of medical devices designed specifically to treat onychomycosis has recently increased, although their mechanism of action is not clear. We evaluated available laser therapies for onychomycosis by reviewing the existing literature. Twenty-two reports, published in peer-reviewed journals and as white papers out of 926 initial search results conveyed enough details to be included in this study. In most cases, the methodology of the trials described in the papers we reviewed was not comprehensive and the reporting of outcomes was not unified. We therefore found it hard to compare different clinical trials to one another. The majority of studies (81.82%) reported using an Nd: YAG laser device to treat onychomycosis. A total of 47.37% of the studies which used a 1064 device (and 47.83% of all studies we reviewed) reported that all treated patients responded positively to laser therapy. A total of 60% of studies reported achieving a complete cure (no clinical symptoms, nor negative mycology) in at least 50% of the treated patients. A low number of adverse events and their mild intensity were consistently reported across all studies, which makes this form of therapy particularly attractive to patients with contraindications for receiving systemic antifungal medication. In order to achieve more unified, comparable studies in the future, we suggest that researchers report a minimum set of outcome measurements: the calculation of the infected nail area pre-and posttreatment, as well as the number of patients achieving mycological, clinical and complete cures.
dc.language.isoen
dc.publisherWILEY
dc.relation.ispartofJOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
dc.subject930-NM LIGHT EXPOSURE
dc.subjectALUMINUM-GARNET LASER
dc.subjectCLASSIFICATION
dc.subjectDermatology
dc.subjectEFFICACY
dc.subjectMILD
dc.subjectMODERATE
dc.titleLaser therapies for onychomycosis - critical evaluation of methods and effectiveness
dc.typereview
dc.identifier.doi10.1111/jdv.13593
dc.identifier.isiISI:000379539800003
dc.description.volume30
dc.description.issue6
dc.description.startpage936
dc.description.endpage942
dc.contributor.orcid0000-0001-5361-9876
dc.contributor.researcheridH-6773-2019
dc.contributor.researcheridAAL-7612-2020
dc.identifier.eissn14683083
dc.publisher.place111 RIVER ST, HOBOKEN 07030-5774, NJ USA
dcterms.isPartOf.abbreviationJ. Eur. Acad. Dermatol. Venereol.
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