DC Field | Value | Language |
dc.contributor.author | Mikhailopulo, IA | |
dc.contributor.author | Kalinichenko, EN | |
dc.contributor.author | Podkopaeva, TL | |
dc.contributor.author | Kelve, M | |
dc.contributor.author | Saarma, M | |
dc.contributor.author | Lidaks, MY | |
dc.contributor.author | Rosemeyer, H | |
dc.contributor.author | Seela, F | |
dc.date.accessioned | 2021-12-23T16:21:18Z | - |
dc.date.available | 2021-12-23T16:21:18Z | - |
dc.date.issued | 1997 | |
dc.identifier.issn | 15257770 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/13810 | - |
dc.description.abstract | An analogue of the 2-5A core trimer containing an 8-(4-aminobutyl)-aminoadenosine (1, A*) residue at the 2'(3')-terminus [2; (2',5')A(2)A*] was synthesized. The conformation of (2',5')A(2)A* was studied by H-1, C-13-NMR, and CD spectroscopy. The (2',5')A(2)A* exhibits very low binding ability to the RNase L of mouse L cells, but slightly enhanced resistance to digestion by SVPD compared to the parent trimer. | |
dc.language.iso | en | |
dc.publisher | TAYLOR & FRANCIS INC | |
dc.relation.ispartof | NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | |
dc.subject | 2-5A | |
dc.subject | ACID | |
dc.subject | ANALOGS | |
dc.subject | ANTI CONFORMATION | |
dc.subject | Biochemistry & Molecular Biology | |
dc.subject | BOND | |
dc.subject | FRAGMENTS | |
dc.subject | NMR | |
dc.subject | NUCLEAR MAGNETIC-RESONANCE | |
dc.subject | NUCLEOTIDES | |
dc.subject | PURINE NUCLEOSIDES | |
dc.title | A 2'->5'-adenylate trimer with a positively charged 2'(3')-terminal 8-(4-aminobutyl)aminoadenosine residue: Synthesis, conformation and RNase L binding | |
dc.type | journal article | |
dc.identifier.doi | 10.1080/07328319708002539 | |
dc.identifier.isi | ISI:A1997YK89500005 | |
dc.description.volume | 16 | |
dc.description.issue | 10-11 | |
dc.description.startpage | 1855 | |
dc.description.endpage | 1873 | |
dc.identifier.eissn | 15322335 | |
dc.publisher.place | 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA | |
dcterms.isPartOf.abbreviation | Nucleosides Nucleotides Nucleic Acids | |
crisitem.author.dept | Institut für Chemie neuer Materialien | - |
crisitem.author.deptid | institute11 | - |
crisitem.author.parentorg | FB 05 - Biologie/Chemie | - |
crisitem.author.grandparentorg | Universität Osnabrück | - |
crisitem.author.netid | RoHe783 | - |