International guidelines for the in vivo assessment of skin properties in non-clinical settings: part 1. pH
DC Element | Wert | Sprache |
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dc.contributor.author | Stefaniak, Aleksandr B. | |
dc.contributor.author | du Plessis, Johan | |
dc.contributor.author | John, Swen M. | |
dc.contributor.author | Eloff, Fritz | |
dc.contributor.author | Agner, Tove | |
dc.contributor.author | Chou, Tzu-Chieh | |
dc.contributor.author | Nixon, Rosemary | |
dc.contributor.author | Steiner, Markus F. C. | |
dc.contributor.author | Kudla, Irena | |
dc.contributor.author | Holness, D. Linn | |
dc.date.accessioned | 2021-12-23T16:23:53Z | - |
dc.date.available | 2021-12-23T16:23:53Z | - |
dc.date.issued | 2013 | |
dc.identifier.issn | 0909752X | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/14702 | - |
dc.description.abstract | Background Skin surface pH is known to influence the dissolution and partitioning of chemicals and may influence exposures that lead to skin diseases. Non-clinical environments (e.g. workplaces) are highly variable, thereby presenting unique measurement challenges that are not typically encountered in clinical settings. Hence, guidelines are needed for consistent measurement of skin surface pH in environments that are difficult to control. Methods An expert workshop was convened at the 5th International Conference on Occupational and Environmental Exposure of Skin to Chemicals to review available data on factors that could influence the determination of skin surface pH in non-clinical settings with emphasis on the workplace as a worst case scenario. Results The key elements of the guidelines are: (i) minimize, to the extent feasible, the influences of relevant endogenous (anatomical position, skin health, time of day), exogenous (hand washing, barrier creams, soaps and detergents, occlusion), environmental (seasonality), and measurement (atmospheric conditions) factors; (ii) report pH measurements results as a difference or percent change (not absolute values) using a measure of central tendency and variability; and (iii) report notable deviations from these guidelines and other relevant factors that may influence measurements. Conclusion Guidelines on the measurement and reporting of skin surface pH in non-clinical settings should promote consistency in data reporting, facilitate inter-comparison of study results, and aid in understanding and preventing occupational skin diseases. | |
dc.description.sponsorship | NIOSH National Occupational Research Agenda Immune and Dermal cross-sector; [CMU98-S-28]; [NSC 97-2314-B-039-022-MY3]; The authors thank S. Dotson and G. Day at NIOSH for critical review of this manuscript. Mention of a specific product or company does not constitute endorsement by the Centers for Disease Control and Prevention. The findings and conclusions in this report are those of the authors and do not necessarily represent the views of NIOSH. Financial support for the workshop on Workplace Measurement of Skin Barrier and Physiology was provided by the NIOSH National Occupational Research Agenda Immune and Dermal cross-sector. T. C. C. was supported by grants CMU98-S-28 and NSC 97-2314-B-039-022-MY3. Participants of the workshop on Workplace Measurement of Skin Barrier and Physiology which was held under the auspices of the 5th International Conference on Occupational and Environmental Exposure of Skin to Chemicals (OEESC): T. Agner (Denmark), V. Arrandale (Canada), D. Burke (Canada), T. C. Chou (Taiwan, R.O.C.), L. Dilworth (Canada), F. C. Eloff (South Africa), H. Harari (United States), T. Hahn (Germany), L. Holness (Canada), S. M. John (Germany), J. Kim (Canada), I. Kudla (Canada), R. Nixon (Australia), J. L. du Plessis (South Africa), A. B. Stefaniak (United States), G. Wozniak (Canada) | |
dc.language.iso | en | |
dc.publisher | WILEY | |
dc.relation.ispartof | SKIN RESEARCH AND TECHNOLOGY | |
dc.subject | allergy | |
dc.subject | BIOPHYSICAL PARAMETERS | |
dc.subject | contact dermatitis | |
dc.subject | Dermatology | |
dc.subject | FACE | |
dc.subject | FOREARM | |
dc.subject | FOREHEAD | |
dc.subject | GENDER | |
dc.subject | irritation | |
dc.subject | NICKEL RELEASE | |
dc.subject | occupational skin diseases | |
dc.subject | RESIDENT FLORA | |
dc.subject | skin absorption | |
dc.subject | skin barrier | |
dc.subject | skin surface pH | |
dc.subject | stratum corneum | |
dc.subject | STRATUM-CORNEUM HYDRATION | |
dc.subject | SURFACE PH | |
dc.subject | sweat | |
dc.subject | TRANSEPIDERMAL WATER-LOSS | |
dc.subject | workplace measurement | |
dc.title | International guidelines for the in vivo assessment of skin properties in non-clinical settings: part 1. pH | |
dc.type | journal article | |
dc.identifier.doi | 10.1111/srt.12016 | |
dc.identifier.isi | ISI:000317937500001 | |
dc.description.volume | 19 | |
dc.description.issue | 2 | |
dc.description.startpage | 59 | |
dc.description.endpage | 68 | |
dc.contributor.orcid | 0000-0002-9634-0637 | |
dc.contributor.orcid | 0000-0003-2554-6918 | |
dc.contributor.orcid | 0000-0001-5122-8492 | |
dc.contributor.orcid | 0000-0002-7543-8299 | |
dc.contributor.researcherid | A-1460-2019 | |
dc.contributor.researcherid | D-2372-2014 | |
dc.identifier.eissn | 16000846 | |
dc.publisher.place | 111 RIVER ST, HOBOKEN 07030-5774, NJ USA | |
dcterms.isPartOf.abbreviation | Skin Res. Technol. | |
dcterms.oaStatus | Green Published, Bronze | |
crisitem.author.orcid | 0000-0001-5406-9458 | - |
crisitem.author.netid | JoSw269 | - |
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geprüft am 06.06.2024