Synthesis of 5-aza-7-deazapurine and 3,7-dideazapurine 2'-deoxyribofuranosides by solid-liquid phase-transfer glycosylation.
| Autor(en): | Seela, F. Rosemeyer, H. Bourgeois, W. |
Stichwörter: | Deoxyribonucleosides; Glycosides; Indicators and Reagents; Purine Nucleosides; deoxyribonucleoside; dyes, reagents, indicators, markers and buffers; glycoside; purine nucleoside, article; chemistry; synthesis, Chemistry; Deoxyribonucleosides; Glycosides; Indicators and Reagents; Purine Nucleosides | Erscheinungsdatum: | 1987 | Journal: | Nucleic acids symposium series | Ausgabe: | 18 | Startseite: | 49 | Seitenende: | 52 | Zusammenfassung: | The 2'-deoxyguanosine isostere 1 as well as the pyrrolo [3,2-c] pyridine 2'-deoxyribofuranosides 2a,b and 3a-d have been synthesized in high yield by solid-liquid phase-transfer glycosylation. It was shown that only the strongly nucleophilic pyrrolo [3,2-c] pyridines formed exclusively beta-2'-deoxyribofuranosides, whereas weakly nucleophilic imidazo [1,2-a]-s-triazines gave mixtures of anomers. |
ISSN: | 02613166 | Externe URL: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023464953&partnerID=40&md5=d2c5d1a2bef9d8b6cafbccacd771f98f |
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