Occlusion effects of glove wearing: Efficacy of a skin protection cream containing aluminium chlorohydrate [Okklusionseffekt von schutzhandschuhen: Effizienz einer aluminiumchlorohydrat-haltigen hautschutzcreme]

Abstract

The efficacy against negative effects of glove wearing of a skin protection cream containing aluminium chlorohydrate was investigated in a randomised and controlled study with 25 healthy subjects. For this purpose, transepidermal water loss (TEWL), hydration of the horny layer (RHF) and skin surface pH were measured before and at regular intervals after 30 min occlusion through glove wearing. Immediately after the occlusion and throughout the duration of the experiment, significantly increased differences with start values before glove wearing were noticed for the test area treated with the skin protection cream in comparison to the untreated area. Alone skin surface pH did not differ significantly between the test and control areas after removing the gloves. From these preliminary results, it may be concluded that increased sweating due to glove wearing could be reduced through a prior treatment of the hands with a skin protection cream containing aluminium chlorohydrate.