Electrophilic substitution at C(7) of a protected 7-deaza-2′- deoxyguanosine - The 2′-deoxyribonucleoside parent analogue of queuosine
| Autor(en): | Ramzaeva, N. Rosemeyer, H. |
Stichwörter: | 7-deazapurine; Eschenmoser's salt; Mannich bases | Erscheinungsdatum: | 2007 | Herausgeber: | MDPI AG | Journal: | MolBank | Volumen: | 2007 | Ausgabe: | 1 | Zusammenfassung: | In this manuscript we report on the regioselective electrophilic substitution at C(7) of 7-[2-deoxy-3,5-bis-O-(2-methylpropanoyl)-β-D- erythro-pentofuranosyl]-2-(formylamino)-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine (2) - a protected precursor of 7-deaza-2′-deoxyguanosine - using N,N-dimethyl-methyleniminium iodide (Eschenmoser's salt) yielding the Mannich compound 4. © 2007 by MDPI. |
ISSN: | 14228599 | DOI: | 10.3390/m522 | Externe URL: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-50849141928&doi=10.3390%2fm522&partnerID=40&md5=dfcb3ca43233300e17f5965674551798 |
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