New possibilities for the structure determination of membrane proteins [Neue Möglichkeiten für die Strukturbestimmung von Membranproteinen]

Autor(en): Gewering, T.
Möller, A. 
Erscheinungsdatum: 2020
Herausgeber: Springer Spektrum
Journal: BioSpektrum
Volumen: 26
Ausgabe: 6
Startseite: 615
Seitenende: 617
Zusammenfassung: 
Membrane proteins establish the connection between the outside and the inside of a cell. Even though 30 percent of proteins in a cell are membrane associated, their structural data is strongly underrepresented due to the high flexibility and low purification yield. The resolution revolution in cryo-EM opened up new opportunities to solve structures of dynamic membrane proteins that can only be purified in small quantities. © 2020, Die Autoren.
ISSN: 09470867
DOI: 10.1007/s12268-020-1469-0
Externe URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092668980&doi=10.1007%2fs12268-020-1469-0&partnerID=40&md5=6f8bede9231db89ef451ec3585b03dd5

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