New possibilities for the structure determination of membrane proteins [Neue Möglichkeiten für die Strukturbestimmung von Membranproteinen]

Autor(en): Gewering, T.
Möller, A. 
Erscheinungsdatum: 2020
Herausgeber: Springer Spektrum
Enthalten in: BioSpektrum
Band: 26
Ausgabe: 6
Startseite: 615
Seitenende: 617
Membrane proteins establish the connection between the outside and the inside of a cell. Even though 30 percent of proteins in a cell are membrane associated, their structural data is strongly underrepresented due to the high flexibility and low purification yield. The resolution revolution in cryo-EM opened up new opportunities to solve structures of dynamic membrane proteins that can only be purified in small quantities. © 2020, Die Autoren.
ISSN: 09470867
DOI: 10.1007/s12268-020-1469-0
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