Parallel DNA containing pyrazolo[3,4-D]pyrimidine analogues of isoguanine
Autor(en): | Seela, F Kroschel, R He, Y |
Stichwörter: | Biochemistry & Molecular Biology | Erscheinungsdatum: | 2001 | Herausgeber: | MARCEL DEKKER INC | Journal: | NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | Volumen: | 20 | Ausgabe: | 4-7 | Startseite: | 1283 | Seitenende: | 1286 | Zusammenfassung: | The phosphoramidites of 8-aza-7-deaza-2'-deoxyisoguanosine (1a) and its bromo derivative 1b as well as of 6-aza-2-deoxyisocytidine and its 5-methyl derivative (3a,b) were synthesized. Parallel-stranded duplexes containing the nucleosides 1a,b show a significantly enhanced duplex stability compared to those containing 2'-deoxyisoguanosine. |
Beschreibung: | XIVth International Roundtable on Nucleosides, Nucleotides and their Biological Applications, SAN FRANCISCO, CALIFORNIA, SEP 10-14, 2000 |
ISSN: | 15257770 | DOI: | 10.1081/NCN-100002537 |
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geprüft am 18.05.2024