Oligonucleotides containing 7- or 8-methyl-7-deazaguanine: Steric requirements of major groove substituents on the DNA structure

Autor(en): Seela, F
Chen, YM
Stichwörter: Chemistry; Chemistry, Multidisciplinary; EQUILIBRIUM
Erscheinungsdatum: 1996
Herausgeber: ROYAL SOC CHEMISTRY
Journal: CHEMICAL COMMUNICATIONS
Ausgabe: 19
Startseite: 2263
Seitenende: 2264
Zusammenfassung: 
Methyl groups in alternating octanucleotides containing 7-methyl-7-deazaguanine and cytosine have steric freedom and maintain the B-DNA structure, whereas the isomeric 8-methyl-7-deazaguanine causes a B-Z transition.
ISSN: 13597345
DOI: 10.1039/cc9960002263

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