On the Morphology of the Drosophila Heart

Autor(en): Rotstein, Barbara
Paululat, Achim 
Stichwörter: Cardiac & Cardiovascular Systems; cardiovascular system; Cardiovascular System & Cardiology; circulatory system; dorsal vessel; Drosophila melanogaster; heart
Erscheinungsdatum: 2016
Herausgeber: MDPI
Journal: JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
Volumen: 3
Ausgabe: 2
Zusammenfassung: 
The circulatory system of Drosophila melanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to name a few examples. In recent years, the Drosophila heart has also attracted the attention of researchers in the field of biomedicine. This development is mainly due to the fact that several genes causing human heart disease are also present in Drosophila, where they play the same or similar roles in heart development, maintenance or physiology as their respective counterparts in humans. This review will attempt to briefly introduce the anatomy of the Drosophila circulatory system and then focus on the different cell types and non-cellular tissue that constitute the heart.
ISSN: 23083425
DOI: 10.3390/jcdd3020015

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