DC Field | Value | Language |
dc.contributor.author | Seela, Frank | |
dc.contributor.author | Ming, Xin | |
dc.contributor.author | Budow, Simone | |
dc.contributor.author | Eickmeier, Henning | |
dc.contributor.author | Reuter, Hans | |
dc.date.accessioned | 2021-12-23T15:58:26Z | - |
dc.date.available | 2021-12-23T15:58:26Z | - |
dc.date.issued | 2007 | |
dc.identifier.issn | 01082701 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/3377 | - |
dc.description.abstract | The title compound [ systematic name: 5-amino-3-(2-deoxy-beta- D-erythro-pentofuranosyl) thiazolo[ 4,5-d] pyrimidine-2,7- (3H, 6H)-dione], C10H12N4O5S, exhibits a syn glycosylic bond conformation, with a torsion angle chi of 61.0 (3)degrees. The furanose moiety adopts the N-type sugar pucker (T-3(4)), with P = 33.0 (5)degrees and tau(m) = 15.1 (1)degrees. The conformation at the exocyclic C4'-C5' bond is ap (trans), with the torsion angle gamma = 176.71 (14)degrees. The extended structure is a three-dimensional hydrogen-bond network involving O-H center dot center dot center dot O and N-H center dot center dot center dot O hydrogen bonds. | |
dc.language.iso | en | |
dc.publisher | BLACKWELL PUBLISHING | |
dc.relation.ispartof | ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | |
dc.subject | 7-THIA-8-OXOGUANOSINE | |
dc.subject | ANTIVIRAL ACTIVITY | |
dc.subject | Chemistry | |
dc.subject | Chemistry, Multidisciplinary | |
dc.subject | Crystallography | |
dc.subject | IMMUNOSTIMULANTS | |
dc.title | 2 `-Deoxyimmunosine: a thiazolo-[4,5-d]pyrimidine nucleoside adopting the syn conformation | |
dc.type | journal article | |
dc.identifier.doi | 10.1107/S010827010703750X | |
dc.identifier.isi | ISI:000249151500032 | |
dc.description.volume | 63 | |
dc.description.issue | 9 | |
dc.description.startpage | O549-O551 | |
dc.contributor.researcherid | H-9847-2014 | |
dc.publisher.place | 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND | |
dcterms.isPartOf.abbreviation | Acta Crystallogr. Sect. C-Cryst. Struct. Commun. | |
crisitem.author.dept | Institut für Chemie neuer Materialien | - |
crisitem.author.deptid | institute11 | - |
crisitem.author.parentorg | FB 05 - Biologie/Chemie | - |
crisitem.author.grandparentorg | Universität Osnabrück | - |
crisitem.author.netid | ReHa636 | - |