5-Methyl-6-aza-2 `-deoxyisocytidine

Abstract

In the title compound, 3-amino-2-(2-deoxy-beta-D-erythro-pentofuranosyl)6- methyl-1,2,4-triazin-5(2H)-one, C9H14N4O4, the conformation of the N-glycosidic bond is high-anti and the 2-deoxyribofuranosyl moiety adopts a North sugar pucker (T-2(3)). The orientation of the exocyclic C-C bond between the -CH2OH group and the five-membered ring is ap (gauche, trans). The crystal packing is such that the nucleobases lie parallel to the ac plane; the planes are connected via hydrogen bonds involving the five-membered ring.