7-deaza-2 `-deoxyguanosines functionalized with 7-(omega-aminoalk-1-ynyl) residues

DC FieldValueLanguage
dc.contributor.authorRamzaeva, N
dc.contributor.authorMittelbach, C
dc.contributor.authorSeela, F
dc.date.accessioned2021-12-23T15:58:47Z-
dc.date.available2021-12-23T15:58:47Z-
dc.date.issued1999
dc.identifier.issn07328311
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/3559-
dc.descriptionXIII International Round Table Conference on Nucleosides, Nucleotides and their Biological Applications, MONTPELLIER, FRANCE, SEP 06-10, 1998
dc.description.abstractThe Pd(0)-catalyzed cross coupling reaction of 7-iodo-7-deaza-2'-deoxyguanosine (1, I(7)c(7)G(d)) With the phthalimido-protected omega-aminoalkines 2a-c gave the compounds 3a-c. They were converted into the phosphoramidite building block 4a-c as well as the phosphonates 5a-c. Compounds 4a and 4c were incorporated into oligodeoxynucleotides of different sequence and their duplex stabilities were measured and compared with those of the unmodified counterparts.
dc.language.isoen
dc.publisherMARCEL DEKKER INC
dc.relation.ispartofNUCLEOSIDES & NUCLEOTIDES
dc.subjectBiochemistry & Molecular Biology
dc.subjectOLIGONUCLEOTIDES
dc.title7-deaza-2 `-deoxyguanosines functionalized with 7-(omega-aminoalk-1-ynyl) residues
dc.typeconference paper
dc.identifier.doi10.1080/07328319908044747
dc.identifier.isiISI:000081805900097
dc.description.volume18
dc.description.issue6-7
dc.description.startpage1439
dc.description.endpage1440
dc.publisher.place270 MADISON AVE, NEW YORK, NY 10016 USA
dcterms.isPartOf.abbreviationNucleosides Nucleotides
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