3-bromo-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1H-pyrazolo[3,4,d]py rimidine-4,6-diamine: a nucleoside which strongly enhances DNA duplex stability
| Autor(en): | Seela, F Sirivolu, VR He, JL Eickmeier, H |
Stichwörter: | BASES; Chemistry; Chemistry, Multidisciplinary; CRYSTAL; Crystallography; DT; HIGH-ANTI CONFORMATION | Erscheinungsdatum: | 2005 | Herausgeber: | BLACKWELL MUNKSGAARD | Journal: | ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | Volumen: | 61 | Ausgabe: | 2 | Startseite: | O67-O69 | Zusammenfassung: | The title compound, C10H13BrN6O3, exhibits an anti glycosylic bond conformation, with an O-C-N-C torsion angle of -105.0 (6)degrees. The pseudorotation phase angle and the amplitude [P = 5.8 (5)degrees and tau(m) = 30.0 (3)degrees, respectively] indicate N-type sugar puckering (T-3(2)). |
ISSN: | 01082701 | DOI: | 10.1107/S0108270104032123 |
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geprüft am 17.05.2024
