8-aza-7-deazapurine DNA: Synthesis and duplex stability of oligonucleotides containing 7-substituted bases

Autor(en): Seela, F
Becher, G
Zulauf, M
Stichwörter: Biochemistry & Molecular Biology
Erscheinungsdatum: 1999
Herausgeber: MARCEL DEKKER INC
Journal: NUCLEOSIDES & NUCLEOTIDES
Volumen: 18
Ausgabe: 6-7
Startseite: 1399
Seitenende: 1400
Zusammenfassung: 
The 7-substituted 8-aza-7-deazapurine phosphoramidites 1a - 3c as well as the phosphoramidite 4a were synthesized. In comparison to the parent purine oligonucleotide duplexes, the 7-substituted 8-aza-7-deazapurine residues lead to a significant duplex stabilization.
Beschreibung: 
XIII International Round Table Conference on Nucleosides, Nucleotides and their Biological Applications, MONTPELLIER, FRANCE, SEP 06-10, 1998
ISSN: 07328311
DOI: 10.1080/07328319908044730

Show full item record

Page view(s)

1
Last Week
1
Last month
1
checked on Mar 4, 2024

Google ScholarTM

Check

Altmetric