Parallel-stranded duplex DNA and self-assembled quartet structures formed by isoguanine and related bases

Autor(en): Seela, F
Wei, CF
Melenewski, A
Feiling, E
Stichwörter: Biochemistry & Molecular Biology; IONOPHORES; ISOGUANOSINE; OLIGONUCLEOTIDES
Erscheinungsdatum: 1998
Herausgeber: MARCEL DEKKER INC
Journal: NUCLEOSIDES & NUCLEOTIDES
Volumen: 17
Ausgabe: 9-11
Startseite: 2045
Seitenende: 2052
Zusammenfassung: 
Parallel-stranded (ps) oligonucleotide duplexes are described containing isoguanine-cytosine and/or 5-methylisocytosine-guanine base pairs. A parallel hybrid is also formed when 5-aza-7-deazaguanine base pairs with guanine while the base pair with isoguanine results in an antiparallel duplex. Oligomers such as d(T(4)isoG(4)T(4)) form self-assembled tetraplexes which show a cation selectivity different from that of the G-quartet.
Beschreibung: 
International Conference on Nucleic Acids and Related Macromolecules: Synthesis, Structure, and Application, ULM, GERMANY, SEP 04-09, 1997
ISSN: 07328311
DOI: 10.1080/07328319808004745

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