ESSENTIAL FATTY-ACIDS IN PATHOGENESIS, PROPHYLAXIS, AND THERAPY OF ATOPIC ECZEMA

DC FieldValueLanguage
dc.contributor.authorMELNIK, B
dc.date.accessioned2021-12-23T16:00:20Z-
dc.date.available2021-12-23T16:00:20Z-
dc.date.issued1995
dc.identifier.issn03445062
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/4339-
dc.description.abstractThe present review deals with the roles of essential fatty acids and thymus-eicosanoids in T-cell maturation with special regard to the atopic condition. Recent evidence indicates that initial immune responses to environmental allergens in early childhood occur against a background of maturational deficiency in CD4+ T-cell function. From animal experiments it can be concluded that essential fatty acids and eicosanoids of the thymus microenvironment play a crucial role in differentiation and maturation of immature T-cells. The deficiency of eicosanoid-precursors, i.e., dihomogammalinolenic acid and arachidonic acid, in the early postnatal period of the newborn at `'genetic risk'' for atopy might contribute to inadequate T-cell maturation and affect the ultimate expression of the atopic immune system.
dc.language.isode
dc.publisherDUSTRI-VERLAG DR KARL FEISTLE
dc.relation.ispartofALLERGOLOGIE
dc.subjectAllergy
dc.subjectATOPIC ECZEMA
dc.subjectATOPY
dc.subjectESSENTIAL FATTY ACIDS
dc.subjectPREVENTION OF ATOPY
dc.subjectT-CELL MATURATION
dc.titleESSENTIAL FATTY-ACIDS IN PATHOGENESIS, PROPHYLAXIS, AND THERAPY OF ATOPIC ECZEMA
dc.typejournal article
dc.identifier.isiISI:A1995QG66300002
dc.description.volume18
dc.description.issue1
dc.description.startpage2
dc.description.endpage6
dc.publisher.placeBAHNHOFSTRABE 9 POSTFACH 49, W-8024 MUNCHEN-DEISENHOFEN, GERMANY
dcterms.isPartOf.abbreviationAllergologie
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