Synthesis and base pairing properties of 9-deazapurine N-7-nucleosides in oligonucleotide duplexes and triplexes

Autor(en): Leonard, P
Wiglenda, T
Seela, F
Stichwörter: Biochemistry & Molecular Biology
Erscheinungsdatum: 2001
Herausgeber: MARCEL DEKKER INC
Journal: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volumen: 20
Ausgabe: 4-7
Startseite: 1279
Seitenende: 1282
Zusammenfassung: 
The 9-deazaguanine N-7-2'-deoxyribofuranoside (3) as well as the bromo and iodo derivatives 4a,b were synthesized and incorporated in oligonculeotide duplexes and triplexes. Their base pairing properties were investigated and compared with those of the parent purine N-7-2'-deoxyribofuanosides.
Beschreibung: 
XIVth International Roundtable on Nucleosides, Nucleotides and their Biological Applications, SAN FRANCISCO, CALIFORNIA, SEP 10-14, 2000
ISSN: 15257770
DOI: 10.1081/NCN-100002536

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