Acetaminophen use: A risk for asthma?
DC Element | Wert | Sprache |
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dc.contributor.author | Allmers, Henning | |
dc.contributor.author | Skudlik, Christoph | |
dc.contributor.author | John, Swen Malte | |
dc.date.accessioned | 2021-12-23T16:00:49Z | - |
dc.date.available | 2021-12-23T16:00:49Z | - |
dc.date.issued | 2009 | |
dc.identifier.issn | 15297322 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/4602 | - |
dc.description.abstract | A growing number of studies show that regular use of acetaminophen (paracetamol) carries a dose-dependent risk of developing allergies in general and asthma in particular and of worsening other respiratory diseases and lung function. The most disturbing finding has come from the population-based Avon Longitudinal Study of Parents and Children, in which use of paracetamol-but not aspirin-in late pregnancy was positively associated with asthma when comparing children whose mothers took paracetamol ``sometimes'' and ``most days/daily'' with those whose mothers never took it. Assuming a causal relationship, the percentage of asthma attributable to paracetamol use in late pregnancy was 7%. In this review, we present data from the most important studies published since 2000. Although the pathophysiology remains unclear, the available data justify a warning to the general public that the uncritical use of over-the-counter acetaminophen can lead to the development of allergies and asthma, even in utero. | |
dc.language.iso | en | |
dc.publisher | CURRENT MEDICINE GROUP | |
dc.relation.ispartof | CURRENT ALLERGY AND ASTHMA REPORTS | |
dc.subject | ADULTS | |
dc.subject | Allergy | |
dc.subject | ASSOCIATION | |
dc.subject | CHILDHOOD | |
dc.subject | DISEASE | |
dc.subject | GLUTATHIONE LEVELS | |
dc.subject | Immunology | |
dc.subject | LUNG | |
dc.subject | PARACETAMOL USE | |
dc.title | Acetaminophen use: A risk for asthma? | |
dc.type | review | |
dc.identifier.doi | 10.1007/s11882-009-0024-3 | |
dc.identifier.isi | ISI:000264676100011 | |
dc.description.volume | 9 | |
dc.description.issue | 2 | |
dc.description.startpage | 164 | |
dc.description.endpage | 167 | |
dc.contributor.researcherid | W-7963-2018 | |
dc.publisher.place | 400 MARKET STREET, STE 700, PHILADELPHIA, PA 19106 USA | |
dcterms.isPartOf.abbreviation | Curr. Allergy Asthma Rep. | |
crisitem.author.dept | Universität Osnabrück | - |
crisitem.author.orcid | 0000-0001-5406-9458 | - |
crisitem.author.netid | JoSw269 | - |
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geprüft am 05.06.2024