DC Element | Wert | Sprache |
dc.contributor.author | Junge, Wolfgang | |
dc.contributor.author | Sielaff, Hendrik | |
dc.contributor.author | Engelbrecht, Siegfried | |
dc.date.accessioned | 2021-12-23T16:01:21Z | - |
dc.date.available | 2021-12-23T16:01:21Z | - |
dc.date.issued | 2009 | |
dc.identifier.issn | 00280836 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/4915 | - |
dc.description.abstract | Adenosine triphosphate (ATP), the universal fuel of the cell, is synthesized from adenosine diphosphate (ADP) and inorganic phosphate (Pi) by `ATP synthase' (FOF1-ATPase). During respiration or photosynthesis, an electrochemical potential difference of protons is set up across the respective membranes. This powers the enzyme's electrical rotary nanomotor (F-O), which drives the chemical nanomotor (F-1) by elastic mechanical-power transmission, producing ATP with high kinetic efficiency. Attempts to understand in detail the mechanisms of torque generation in this simple and robust system have been both aided and complicated by a wealth of sometimes conflicting data. | |
dc.description.sponsorship | Deutsche ForschungsgemeinschaftGerman Research Foundation (DFG); VolkswagenstiftungVolkswagen; European UnionEuropean Commission; Fonds der Chemie; We thank D. Cherepanov and O. P nke for their contributions to elastic coupling, G. Hikade and H. Kenneweg for technical assistance, and J. Weber for discussions. We acknowledge financial support from Deutsche Forschungsgemeinschaft, Volkswagenstiftung, European Union and Fonds der Chemie. | |
dc.language.iso | en | |
dc.publisher | NATURE PUBLISHING GROUP | |
dc.relation.ispartof | NATURE | |
dc.subject | B-SUBUNIT | |
dc.subject | BOVINE HEART-MITOCHONDRIA | |
dc.subject | C SUBUNIT OLIGOMER | |
dc.subject | CATALYTIC SITES | |
dc.subject | COLI ATP SYNTHASE | |
dc.subject | COUPLING PROTON MOVEMENTS | |
dc.subject | ESCHERICHIA-COLI | |
dc.subject | F-ATPASE | |
dc.subject | Multidisciplinary Sciences | |
dc.subject | NUCLEOTIDE DEPENDENCE | |
dc.subject | OXIDATIVE-PHOSPHORYLATION | |
dc.subject | Science & Technology - Other Topics | |
dc.title | Torque generation and elastic power transmission in the rotary F0F1-ATPase | |
dc.type | review | |
dc.identifier.doi | 10.1038/nature08145 | |
dc.identifier.isi | ISI:000266243700034 | |
dc.description.volume | 459 | |
dc.description.issue | 7245 | |
dc.description.startpage | 364 | |
dc.description.endpage | 370 | |
dc.contributor.orcid | 0000-0001-5231-7286 | |
dc.contributor.researcherid | F-6289-2012 | |
dc.publisher.place | MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND | |
dcterms.isPartOf.abbreviation | Nature | |
crisitem.author.dept | FB 05 - Biologie/Chemie | - |
crisitem.author.deptid | fb05 | - |
crisitem.author.parentorg | Universität Osnabrück | - |
crisitem.author.netid | JuWo587 | - |