6-aza-2 `-deoxy-2 `-arabinofluorouridine, a 2 `-deoxyribonucleoside with an N-sugar conformation in the solid state and in solution
DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Seela, F | |
dc.contributor.author | Chittepu, P | |
dc.contributor.author | He, JL | |
dc.contributor.author | Eickmeier, H | |
dc.date.accessioned | 2021-12-23T16:01:39Z | - |
dc.date.available | 2021-12-23T16:01:39Z | - |
dc.date.issued | 2004 | |
dc.identifier.issn | 01082701 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/5086 | - |
dc.description.abstract | In the title compound, 2-( 2- deoxy- 2- fluoro- beta- d- arabinofuranosyl)1,2,4- triazine- 3,5( 2H, 4H)- dione, C8H10FN3O5, the torsion angle of the N- glycosylic bond is anti [ chi = 125.37 ( 13)degrees]. The furanose moiety adopts the N- type sugar pucker ( T-3(2)), with P = 359.2degrees and tau(m) = 31.4degrees. The conformation around the C4' - C5' bond is antiperiplanar ( trans), with a torsion angle gamma of 177.00 ( 11)degrees. A network is formed via hydrogen bonds from the nucleobases to the sugar residues, as well as through hydrogen bonds between the sugar moieties. | |
dc.language.iso | en | |
dc.publisher | BLACKWELL MUNKSGAARD | |
dc.relation.ispartof | ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | |
dc.subject | ANTIVIRAL NUCLEOSIDES | |
dc.subject | Chemistry | |
dc.subject | Chemistry, Multidisciplinary | |
dc.subject | CRYSTAL | |
dc.subject | Crystallography | |
dc.subject | DUPLEX | |
dc.subject | RNA | |
dc.subject | STABILITY | |
dc.title | 6-aza-2 `-deoxy-2 `-arabinofluorouridine, a 2 `-deoxyribonucleoside with an N-sugar conformation in the solid state and in solution | |
dc.type | journal article | |
dc.identifier.doi | 10.1107/S0108270104023649 | |
dc.identifier.isi | ISI:000225558400038 | |
dc.description.volume | 60 | |
dc.description.issue | 12 | |
dc.description.startpage | O884-O886 | |
dc.publisher.place | 35 NORRE SOGADE, PO BOX 2148, DK-1016 COPENHAGEN, DENMARK | |
dcterms.isPartOf.abbreviation | Acta Crystallogr. Sect. C-Cryst. Struct. Commun. |
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geprüft am 01.06.2024