Parallel-stranded DNA formed by new base pairs related to the isoguanine-cytosine or isocytosine-guanine motifs

Autor(en): Seela, F
Wei, CF
Melenewski, A
He, Y
Kroschel, R
Feiling, E
Stichwörter: 2'-DEOXYISOGUANOSINE; Biochemistry & Molecular Biology; OLIGONUCLEOTIDES
Erscheinungsdatum: 1999
Herausgeber: MARCEL DEKKER INC
Journal: NUCLEOSIDES & NUCLEOTIDES
Volumen: 18
Ausgabe: 6-7
Startseite: 1543
Seitenende: 1548
Zusammenfassung: 
Parallel-stranded (ps) oligonucleotide duplexes containing several new base pairs formed between 7-deazaisoguanine and cytosine, 8-aza-7-deaza-isoguanine and cytosine, and 5-aza-7-deaza guanine and guanine are described. The stability of the ps-hybrids increased if the duplex contains 8-aza-7-deazaisoguanine instead of isoguanine and is decreased by 7-deazaisoguanine incorporation. The purine-purine base pair between 5-aza-7-deazaguanine and guanine was found to be more stable than that of 5-methylisocytosine with guanine.
Beschreibung: 
XIII International Round Table Conference on Nucleosides, Nucleotides and their Biological Applications, MONTPELLIER, FRANCE, SEP 06-10, 1998
ISSN: 07328311
DOI: 10.1080/07328319908044781

Show full item record

Page view(s)

1
Last Week
0
Last month
0
checked on Feb 24, 2024

Google ScholarTM

Check

Altmetric