DC Field | Value | Language |
dc.contributor.author | SEELA, F | |
dc.contributor.author | WENZEL, T | |
dc.date.accessioned | 2021-12-23T16:02:33Z | - |
dc.date.available | 2021-12-23T16:02:33Z | - |
dc.date.issued | 1993 | |
dc.identifier.issn | 03855414 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/5472 | - |
dc.description.abstract | The synthesis of the 3'-[(2-cyanoethyl)diisopropylphosphoramidite] (3b) and the 3'-phosphonate (3a) of 1-deaza-2'-deoxyadenosine (1b) is described. For this purpose compound lb was protected at the 6-amino group with a benzoyl residue. Ensuing 4,4'-dimethoxytritylation of lb and phosphitylation afforded the P(III) derivatives(3a) and (3b). They were successfully employed in solid-phase oligodeoxyribonucleotide synthesis of d(c1A-c1A-c1A-A-A-A) (6). C-13-Nmr and N-15-nmr spectra of the compounds (1-5) are discussed. | |
dc.language.iso | en | |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | |
dc.relation.ispartof | HETEROCYCLES | |
dc.subject | Chemistry | |
dc.subject | Chemistry, Organic | |
dc.subject | DEOXYNUCLEOSIDES | |
dc.subject | DNA | |
dc.subject | RIBONUCLEOSIDES | |
dc.title | 1-DEAZA-2'-DEOXYADENOSINE - PHOSPHONATE AND PHOSPHORAMIDITE BUILDING-BLOCKS FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS | |
dc.type | journal article | |
dc.identifier.doi | 10.3987/COM-92-6214 | |
dc.identifier.isi | ISI:A1993KH49500004 | |
dc.description.volume | 36 | |
dc.description.issue | 2 | |
dc.description.startpage | 237 | |
dc.description.endpage | 242 | |
dc.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND OX5 1GB | |
dcterms.isPartOf.abbreviation | Heterocycles | |