CALCIUM-DEPENDENT TRANSIENT POTASSIUM OUTWARD CURRENT IN THE MARINE CILIATE EUPLOTES-VANNUS

DC FieldValueLanguage
dc.contributor.authorKRUPPEL, T
dc.contributor.authorWESTERMANN, R
dc.contributor.authorLUEKEN, W
dc.date.accessioned2021-12-23T16:02:34Z-
dc.date.available2021-12-23T16:02:34Z-
dc.date.issued1991
dc.identifier.issn00063002
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/5483-
dc.description.abstractIn the marine hypotrichous ciliate Euplotes vannus, the transient K+ outward current, I(K fast), was studied by use of a single-microelectrode voltage-clamp equipment. Activation and inactivation kinetics, and steady-state inactivation are comparable to the properties of A-currents. Not typical for this type of current is its insensitivity to either 4-AP or 3,4-AP and its Ca2+ dependence which was derived from its inhibition by either extracellular Cd2+, La3+, D-600, or by intracellular BAPTA. Actual amplitudes of I(K fast) were obtained from a composite current, by subtraction of early parts of a slowly activating K+ current, I(K slow), and of the early, transient Ca2+ inward current, I(Ca fast), that is typical for ciliates. I(K fast) counteracts I(Ca fast) during the first milliseconds after onset of depolarization such that the composite current is purely outward directed.
dc.language.isoen
dc.publisherELSEVIER SCIENCE BV
dc.relation.ispartofBIOCHIMICA ET BIOPHYSICA ACTA
dc.subject(E-VANNUS)
dc.subjectA-CURRENT
dc.subjectBiochemistry & Molecular Biology
dc.subjectBiophysics
dc.subjectCALCIUM CURRENT
dc.subjectCARDIAC PURKINJE-FIBERS
dc.subjectCOMPONENTS
dc.subjectCONJUGATION
dc.subjectHYPOTRICHIDA
dc.subjectMEMBRANE CURRENT
dc.subjectNEURONS
dc.subjectPOTASSIUM CURRENT
dc.subjectTRANSIENT OUTWARD CURRENT
dc.subjectVOLTAGE CLAMP
dc.titleCALCIUM-DEPENDENT TRANSIENT POTASSIUM OUTWARD CURRENT IN THE MARINE CILIATE EUPLOTES-VANNUS
dc.typejournal article
dc.identifier.doi10.1016/0005-2736(91)90392-L
dc.identifier.isiISI:A1991FD38800011
dc.description.volume1062
dc.description.issue2
dc.description.startpage193
dc.description.endpage198
dc.publisher.placePO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
dcterms.isPartOf.abbreviationBiochim. Biophys. Acta
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