The insect plasma membrane H+V-ATPase: Intra-, inter-, and supramolecular aspects

DC FieldValueLanguage
dc.contributor.authorWieczorek, H
dc.contributor.authorHuss, M
dc.contributor.authorMerzendorfer, H
dc.contributor.authorReineke, S
dc.contributor.authorVitavska, O
dc.contributor.authorZeiske, W
dc.date.accessioned2021-12-23T16:02:43Z-
dc.date.available2021-12-23T16:02:43Z-
dc.date.issued2003
dc.identifier.issn0145479X
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/5579-
dc.description.abstractThe plasma membrane H+ V-ATPase from the midgut of larval Manduca sexta, commonly called the tobacco hornworm, is the sole energizer of epithelial ion transport in this tissue, being responsible for the alkalinization of the gut lumen up to a pH of more than 11 and for any active ion movement across the epithelium. This minireview deals with those topics of our recent research on this enzyme that may contribute novel aspects to the biochemistry and physiology of V-ATPases. Our research approaches include intramolecular aspects such as subunit topology and the inhibition by macrolide antibiotics, intermolecular aspects such as the hormonal regulation of V-ATPase biosynthesis and the interaction of the V-ATPase with the actin cytoskeleton, and supramolecular aspects such as the interactions of V-ATPase, K+/H+ antiporter, and ion channels, which all function as an ensemble in the transepithelial movement of potassium ions.
dc.language.isoen
dc.publisherSPRINGER/PLENUM PUBLISHERS
dc.relation.ispartofJOURNAL OF BIOENERGETICS AND BIOMEMBRANES
dc.subjectactin
dc.subjectACTIN CYTOSKELETON
dc.subjectbafilomycin
dc.subjectBINDING-SITE
dc.subjectBiophysics
dc.subjectCell Biology
dc.subjectconcanamycin
dc.subjectinsects
dc.subjectK+ TRANSPORT
dc.subjectK+/H+ ANTIPORT
dc.subjectManduca sexta
dc.subjectMANDUCA-SEXTA MIDGUT
dc.subjectmidgut
dc.subjectPOSTERIOR MIDGUT
dc.subjectPROTON PUMP
dc.subjectregulation of biosynthesis
dc.subjectsubunit topology
dc.subjectTOBACCO HORNWORM MIDGUT
dc.subjecttransepithelial K+ transport
dc.subjectV-ATPASE
dc.subjectvacuolar ATPase
dc.subjectYEAST VACUOLAR
dc.titleThe insect plasma membrane H+V-ATPase: Intra-, inter-, and supramolecular aspects
dc.typejournal article
dc.identifier.doi10.1023/A:1025733016473
dc.identifier.isiISI:000185301900009
dc.description.volume35
dc.description.issue4
dc.description.startpage359
dc.description.endpage366
dc.identifier.eissn15736881
dc.publisher.place233 SPRING ST, NEW YORK, NY 10013 USA
dcterms.isPartOf.abbreviationJ. Bioenerg. Biomembr.
crisitem.author.deptFB 05 - Biologie/Chemie-
crisitem.author.deptUniversität Osnabrück-
crisitem.author.deptFB 05 - Biologie/Chemie-
crisitem.author.deptFB 05 - Biologie/Chemie-
crisitem.author.deptidfb05-
crisitem.author.deptidfb05-
crisitem.author.deptidfb05-
crisitem.author.parentorgUniversität Osnabrück-
crisitem.author.parentorgUniversität Osnabrück-
crisitem.author.parentorgUniversität Osnabrück-
crisitem.author.netidWiHe990-
crisitem.author.netidHuMa001-
crisitem.author.netidMeHa731-
crisitem.author.netidViOl437-
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