Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases
| Autor(en): | Drose, S Altendorf, K |
Stichwörter: | ADENOSINE-TRIPHOSPHATASE; ATP-binding cassette (ABC) transporter; Biology; BONE-RESORPTION; CULTURED-CELLS; ESCHERICHIA-COLI; KDP-ATPASE; Life Sciences & Biomedicine - Other Topics; MACROLIDE ANTIBIOTICS; METABOLIC PRODUCTS; P-ATPase; PLASMA-MEMBRANE; plecomacrolide antibiotics; PROTON PUMP; V-ATPase; vacuolar compartments; VACUOLAR H+-ATPASE | Erscheinungsdatum: | 1997 | Herausgeber: | COMPANY OF BIOLOGISTS LTD | Journal: | JOURNAL OF EXPERIMENTAL BIOLOGY | Volumen: | 200 | Ausgabe: | 1 | Startseite: | 1 | Seitenende: | 8 | Zusammenfassung: | Bafilomycins and concanamycins, two groups of the plecomacrolide-defined class of macrolide antibiotics, have recently been recognized as important tools for studying the physiological role of vacuolar-type, proton-translocating ATPases (V-ATPases) and ATPases with phosphorylated states (P-ATPases) in animal and plant cells as well as in yeast, fungi and bacteria. The following review will give an account of the classification and function of these antibiotics. |
ISSN: | 00220949 |
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