The DNA-stabilising nucleoside 7-iodo-2'-deoxytubercidin: Its structure in the solid state and in solution
DC Element | Wert | Sprache |
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dc.contributor.author | Seela, F | |
dc.contributor.author | Zulauf, M | |
dc.contributor.author | Rosemeyer, H | |
dc.contributor.author | Reuter, H | |
dc.date.accessioned | 2021-12-23T16:03:22Z | - |
dc.date.available | 2021-12-23T16:03:22Z | - |
dc.date.issued | 1996 | |
dc.identifier.issn | 1472779X | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/5947 | - |
dc.description.abstract | The crystal structure of 7-iodo-2'-deoxytubercidin 2 has been determined and was compared with those of 2'-deoxytubercidin 3 and 2'-deoxyadenosine 4, The bulky 7-iodo substituent lies 13.2 pm below and the nitrogen of the 6-amino group 5.5 pm above the 7-deazapurine plane, The puckering of compound 2 is (3).E while compound 3 shows a T-2'(3') sugar pucker. The conformation in aqueous solution, determined by H-1 NMR spectroscopy, is only slightly different, showing a (2')E conformation, The glycosylic bond torsion angle is anti in all cases. | |
dc.language.iso | en | |
dc.publisher | ROYAL SOC CHEMISTRY | |
dc.relation.ispartof | JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 | |
dc.subject | 2'-DEOXYTUBERCIDIN | |
dc.subject | Chemistry | |
dc.subject | Chemistry, Organic | |
dc.subject | Chemistry, Physical | |
dc.subject | NUCLEIC-ACIDS | |
dc.subject | OLIGONUCLEOTIDES | |
dc.title | The DNA-stabilising nucleoside 7-iodo-2'-deoxytubercidin: Its structure in the solid state and in solution | |
dc.type | journal article | |
dc.identifier.doi | 10.1039/p29960002373 | |
dc.identifier.isi | ISI:A1996VT28800022 | |
dc.description.issue | 11 | |
dc.description.startpage | 2373 | |
dc.description.endpage | 2376 | |
dc.publisher.place | THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND | |
dcterms.isPartOf.abbreviation | J. Chem. Soc.-Perkin Trans. 2 | |
crisitem.author.dept | Institut für Chemie neuer Materialien | - |
crisitem.author.dept | Institut für Chemie neuer Materialien | - |
crisitem.author.deptid | institute11 | - |
crisitem.author.deptid | institute11 | - |
crisitem.author.parentorg | FB 05 - Biologie/Chemie | - |
crisitem.author.parentorg | FB 05 - Biologie/Chemie | - |
crisitem.author.grandparentorg | Universität Osnabrück | - |
crisitem.author.grandparentorg | Universität Osnabrück | - |
crisitem.author.netid | RoHe783 | - |
crisitem.author.netid | ReHa636 | - |
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geprüft am 18.05.2024