Regioisomeric 4-nitroindazole N-1- and N-2-(beta-D-ribonucleosides)
Autor(en): | Seela, F Peng, XH Eickmeier, H Reuter, H |
Stichwörter: | Chemistry; Chemistry, Multidisciplinary; Crystallography; GLYCOSYLATION | Erscheinungsdatum: | 2004 | Herausgeber: | BLACKWELL MUNKSGAARD | Journal: | ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | Volumen: | 60 | Ausgabe: | 1 | Startseite: | O94-O97 | Zusammenfassung: | The structures of the isomeric nucleosides 4-nitro-1-(beta-D-ribofuranosyl)-1H- indazole, C12H13N3O6, ( I), and 4-nitro-2( beta-D-ribofuranosyl)-2H-indazole, C12H13N3O6, (II), have been determined. For compound ( I), the conformation of the glycosylic bond is anti [chi = -93.6 (6)degrees] and the sugar puckering is C2'-exo - C3'-endo. Compound (II) shows two conformations in the crystalline state which differ mainly in the sugar pucker; type 1 adopts the C2'-endo - C3'-exo sugar puckering associated with a syn base orientation [chi = 43.7 (6) degrees] and type 2 shows C2'-exo-C3'-endo sugar puckering accompanied by a somewhat different syn base orientation [chi = 13.8 (6) degrees]. |
ISSN: | 01082701 | DOI: | 10.1107/S0108270103026556 |
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