The SLC45 gene family of putative sugar transporters
DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Vitavska, Olga | |
dc.contributor.author | Wieczorek, Helmut | |
dc.date.accessioned | 2021-12-23T16:03:49Z | - |
dc.date.available | 2021-12-23T16:03:49Z | - |
dc.date.issued | 2013 | |
dc.identifier.issn | 00982997 | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/6219 | - |
dc.description.abstract | According to the classic point of view, transport of sugars across animal plasma membranes is performed by two families of transporters. Secondary active transport occurs via Na+ symporters of the SLC5 gene family, while passive transport occurs via facilitative transporters of the SLC2 family. In recent years a new family appeared in the scenery which was called the SLC45 gene family of putative sugar transporters, mainly because of obvious similarities to plant sucrose transporters. The SLC45 family consists of only four members that have been denominated Al-A4. These members apparently have counterparts in all vertebrates. Moreover, their amino acid sequences reveal close homologies also to respective invertebrate proteins such as a recently detected sucrose transporter in Drosophila, and suggest a phylogenetic relationship also to corresponding proteins from plants, fungi and bacteria. This minireview describes the molecular features of its members with a focus on their possible role as sugar transporters. (C) 2012 Elsevier Ltd. All rights reserved. | |
dc.description.sponsorship | Swiss National Science Foundation through the National Center of Competence in Research (NCCR) TransCure, University of Bern, Switzerland; Publication in part sponsored by the Swiss National Science Foundation through the National Center of Competence in Research (NCCR) TransCure, University of Bern, Switzerland; Director Matthias A. Hediger; Web: http://www.transcure.ch. | |
dc.language.iso | en | |
dc.publisher | ELSEVIER SCIENCE BV | |
dc.relation.ispartof | MOLECULAR ASPECTS OF MEDICINE | |
dc.subject | Biochemistry & Molecular Biology | |
dc.subject | Glucose | |
dc.subject | IDENTIFICATION | |
dc.subject | MATP GENE | |
dc.subject | Medicine, Research & Experimental | |
dc.subject | MELANOMA | |
dc.subject | MUTATION | |
dc.subject | OCULOCUTANEOUS ALBINISM | |
dc.subject | POLYMORPHISMS | |
dc.subject | PROSTATE-CANCER | |
dc.subject | PROTEIN | |
dc.subject | Research & Experimental Medicine | |
dc.subject | SKIN COLOR | |
dc.subject | SLC45 | |
dc.subject | Sucrose | |
dc.subject | Sugar transport | |
dc.subject | Sugar transporter | |
dc.subject | UNDERWHITE GENE | |
dc.title | The SLC45 gene family of putative sugar transporters | |
dc.type | review | |
dc.identifier.doi | 10.1016/j.mam.2012.05.014 | |
dc.identifier.isi | ISI:000318258200042 | |
dc.description.volume | 34 | |
dc.description.issue | 2-3, SI | |
dc.description.startpage | 655 | |
dc.description.endpage | 660 | |
dc.publisher.place | PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS | |
dcterms.isPartOf.abbreviation | Mol. Asp. Med. | |
crisitem.author.dept | FB 05 - Biologie/Chemie | - |
crisitem.author.dept | FB 05 - Biologie/Chemie | - |
crisitem.author.deptid | fb05 | - |
crisitem.author.deptid | fb05 | - |
crisitem.author.parentorg | Universität Osnabrück | - |
crisitem.author.parentorg | Universität Osnabrück | - |
crisitem.author.netid | ViOl437 | - |
crisitem.author.netid | WiHe990 | - |
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geprüft am 02.06.2024