Hydrophilically stabilized gold nanostars as SERS labels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy

DC ElementWertSprache
dc.contributor.authorSchuetz, Max
dc.contributor.authorSteinigeweg, Dennis
dc.contributor.authorSalehi, Mohammad
dc.contributor.authorKoempe, Karsten
dc.contributor.authorSchluecker, Sebastian
dc.date.accessioned2021-12-23T16:04:25Z-
dc.date.available2021-12-23T16:04:25Z-
dc.date.issued2011
dc.identifier.issn13597345
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/6420-
dc.description.abstractA biocompatible, seed-mediated synthesis of monodisperse similar to 60 nm gold nanostars, followed by hydrophilic stabilization with ethylene glycol-modified Raman reporter molecules, is presented. Their application as SERS labels for imaging of the tumor suppressor p63 in prostate biopsies by immuno-SERS microscopy is demonstrated.
dc.description.sponsorshipEuropean UnionEuropean Commission [W2-80111700]; German Research Foundation (DFG)German Research Foundation (DFG) [INST 190/128-1]; Financial support from the European Union and the State of Lower Saxony (EFRE, project no. W2-80111700) and the German Research Foundation (DFG, INST 190/128-1) is acknowledged. Thanks to PD Dr J. Packeisen (Medical Center, Osnabruck), Prof. P. Strobel and Prof. A. Marx (Institute of Pathology, University Hospital Mannheim). We also thank Jaeseung Hahn, a DAAD RISE internship student, for technical assistance and Prof. M. Haase (Institute of Chemistry, University of Osnabruck) for access to HR-TEM.
dc.language.isoen
dc.publisherROYAL SOC CHEMISTRY
dc.relation.ispartofCHEMICAL COMMUNICATIONS
dc.subjectChemistry
dc.subjectChemistry, Multidisciplinary
dc.subjectNANOPARTICLES
dc.titleHydrophilically stabilized gold nanostars as SERS labels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy
dc.typejournal article
dc.identifier.doi10.1039/c0cc05229a
dc.identifier.isiISI:000288610500049
dc.description.volume47
dc.description.issue14
dc.description.startpage4216
dc.description.endpage4218
dc.contributor.orcid0000-0002-0481-2829
dc.contributor.orcid0000-0003-4790-4616
dc.contributor.researcheridAAA-4466-2020
dc.contributor.researcheridD-9524-2018
dc.contributor.researcheridC-2113-2013
dc.contributor.researcheridD-1031-2010
dc.identifier.eissn1364548X
dc.publisher.placeTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
dcterms.isPartOf.abbreviationChem. Commun.
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