Association between tobacco smoking and prognosis of occupational hand eczema : a prospective cohort study
Autor(en): | Brans, Richard Weisshaar, Elke Scheidt, Reginald Diepgen, Thomas L. |
Erscheinungsdatum: | 2014 | Herausgeber: | Wiley-Blackwell Blackwell Science |
Journal: | British journal of dermatology : BJD ; the journal of the British Association of Dermatologists | Volumen: | 171 | Ausgabe: | 5 | Startseite: | 1108 | Seitenende: | 1115 | Zusammenfassung: | Background: Hand eczema (HE) is a common occupational skin disease. Tobacco smoking is known to be associated with adverse cutaneous effects. However, its influence on the prognosis of occupational HE has not yet been studied. Objectives: To evaluate relations between smoking status, severity and prognosis of occupational HE in patients taking part in an interdisciplinary tertiary individual prevention programme (TIP). Methods: In a prospective, multicentre, cohort study 1608 patients with occupational HE taking part in a TIP were recruited and followed up for 3 years. The clinical and self-reported outcome data of smokers and nonsmokers were compared. Results: Nonsmokers and smokers were equally distributed. During the TIP, the average self-reported daily cigarette consumption and the severity of HE decreased significantly (P < 0·01). However, at all time points HE was significantly more severe in smokers than in nonsmokers. This association was not dependent on the self-reported number of cigarettes smoked daily. Smokers had significantly more days of absence from work due to occupational HE than nonsmokers in the year before the TIP (P < 0·01) and in the following year (P = 0·02). After the TIP, smokers reported significantly more often that they had to give up their occupation (P = 0·02) than nonsmokers. Conclusions: The severity of occupational HE is increased in smokers. Tobacco smoking is associated with a higher number of days of absence from work and with not staying in the workforce owing to occupational HE. Thus, smoking confers a worse prognosis and interferes with the outcome of prevention programmes. |
Externe URL: | https://opac.k10plus.de/DB=2.299/PPN?PPN=1727742915 volltext:%20https://doi.org/10.1111/bjd.13169 volltext:%20https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.13169 |
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