Gold DNA-conjugates: Ion specific self-assembly of gold nanoparticles via the dG-quartet

Autor(en): Seela, F
Jawalekar, AM
Chi, LF
Zhong, DY
Fuchs, H
Stichwörter: Biochemistry & Molecular Biology; DNA; G-quartet; gold-nanoparticles; QUADRUPLEX; self-assembly
Erscheinungsdatum: 2005
Herausgeber: TAYLOR & FRANCIS INC
Journal: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volumen: 24
Ausgabe: 5-7, SI
Startseite: 843
Seitenende: 846
Zusammenfassung: 
The Oxytricha telomere DNA hairpin 5'-d(G(4)T(4)G(4)) immobilized on 13 nm gold nanoparticles forms a supramolecular assembly via dG-quartets, as determined by the color change and by SEM. The aggregation is ion-dependent and selective for sodium ions. K+ is less efficient while Li+ and Cs+ do not drive the aggregation. This work is the first effort exploring the use of secondary structures of DNA (quadruplexes) for producing self-assemblies of gold nanoparticles.
Beschreibung: 
16th International Roundtable of the International-Society-for-Nucleosides-Nucleotides-and-Nucleic-Acids (IS3NA), Univ Minnesota, Ctr Drug Design, Minneapolis, MN, SEP 12-16, 2004
ISSN: 15257770
DOI: 10.1081/NCN-200060322

Show full item record

Page view(s)

2
Last Week
0
Last month
0
checked on Mar 1, 2024

Google ScholarTM

Check

Altmetric