Pan-European study of genotypes and phenotypes in the Arabidopsis relative Cardamine hirsuta reveals how adaptation, demography, and development shape diversity patterns
Autor(en): | Baumgarten, Lukas Pieper, Bjorn Song, Baoxing Mane, Sebastien Lempe, Janne Lamb, Jonathan Cooke, Elizabeth L. Srivastava, Rachita Struett, Stefan Zanko, Danijela Casimiro, Pedro G. P. Hallab, Asis Cartolano, Maria Tattersall, Alexander D. Huettel, Bruno Filatov, Dmitry A. Pavlidis, Pavlos Neuffer, Barbara Bazakos, Christos Schaefer, Hanno Mott, Richard Gan, Xiangchao Alonso-Blanco, Carlos Laurent, Stefan Tsiantis, Miltos |
Stichwörter: | ALLELIC VARIATION; Biochemistry & Molecular Biology; Biology; CLIMATE SURFACES; FLOWERING-LOCUS-C; FRIGIDA; GENETIC-VARIATION; GENOME-WIDE ASSOCIATION; HISTORY; Life Sciences & Biomedicine - Other Topics; NATURAL VARIATION; THALIANA; TREHALOSE 6-PHOSPHATE | Erscheinungsdatum: | 2023 | Herausgeber: | PUBLIC LIBRARY SCIENCE | Journal: | PLOS BIOLOGY | Volumen: | 21 | Ausgabe: | 7 | Zusammenfassung: | We study natural DNA polymorphisms and associated phenotypes in the Arabidopsis relative Cardamine hirsuta. We observed strong genetic differentiation among several ancestry groups and broader distribution of Iberian relict strains in European C. hirsuta compared to Arabidopsis. We found synchronization between vegetative and reproductive development and a pervasive role for heterochronic pathways in shaping C. hirsuta natural variation. A single, fast-cycling ChFRIGIDA allele evolved adaptively allowing range expansion from glacial refugia, unlike Arabidopsis where multiple FRIGIDA haplotypes were involved. The Azores islands, where Arabidopsis is scarce, are a hotspot for C. hirsuta diversity. We identified a quantitative trait locus (QTL) in the heterochronic SPL9 transcription factor as a determinant of an Azorean morphotype. This QTL shows evidence for positive selection, and its distribution mirrors a climate gradient that broadly shaped the Azorean flora. Overall, we establish a framework to explore how the interplay of adaptation, demography, and development shaped diversity patterns of 2 related plant species. |
ISSN: | 1544-9173 | DOI: | 10.1371/journal.pbio.3002191 |
Show full item record