Phosphoramidites and oligonucleotides containing 7-deazapurines and pyrimidines carrying aminopropargyl side chains
Autor(en): | Seela, F Ramzaeva, N Leonard, P Chen, Y Debelak, H Feiling, E Kroschel, R Zulauf, M Wenzel, T Frohlich, T Kostrzewa, M |
Stichwörter: | 7-DEAZA-2'-DEOXYGUANOSINES; Biochemistry & Molecular Biology | Erscheinungsdatum: | 2001 | Herausgeber: | TAYLOR & FRANCIS INC | Journal: | NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | Volumen: | 20 | Ausgabe: | 4-7 | Startseite: | 1421 | Seitenende: | 1424 | Zusammenfassung: | The synthesis of phosphoramidites containing 7-deazaguanine, 7-deazaadenine, uracil and cytosine carrying aminopropargyl chains is described. The corresponding oligonucleotides are stabilized in duplexes thermally as well as against degradation by exonucleases. |
Beschreibung: | 14th International Roundtable on Nucleosides, Nucleotides and their Biological Applications, SAN FRANCISCO, CA, SEP 10-14, 2000 |
ISSN: | 15257770 | DOI: | 10.1081/NCN-100002568 |
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geprüft am 20.05.2024