Phosphoramidites and oligonucleotides containing 7-deazapurines and pyrimidines carrying aminopropargyl side chains

Autor(en): Seela, F
Ramzaeva, N
Leonard, P
Chen, Y
Debelak, H
Feiling, E
Kroschel, R
Zulauf, M
Wenzel, T
Frohlich, T
Kostrzewa, M
Stichwörter: 7-DEAZA-2'-DEOXYGUANOSINES; Biochemistry & Molecular Biology
Erscheinungsdatum: 2001
Herausgeber: TAYLOR & FRANCIS INC
Journal: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volumen: 20
Ausgabe: 4-7
Startseite: 1421
Seitenende: 1424
Zusammenfassung: 
The synthesis of phosphoramidites containing 7-deazaguanine, 7-deazaadenine, uracil and cytosine carrying aminopropargyl chains is described. The corresponding oligonucleotides are stabilized in duplexes thermally as well as against degradation by exonucleases.
Beschreibung: 
14th International Roundtable on Nucleosides, Nucleotides and their Biological Applications, SAN FRANCISCO, CA, SEP 10-14, 2000
ISSN: 15257770
DOI: 10.1081/NCN-100002568

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