pH-dependent assembly of DNA-gold nanoparticles based on the i-motif

DC FieldValueLanguage
dc.contributor.authorSeela, Frank
dc.contributor.authorBudow, Simone
dc.date.accessioned2021-12-23T16:06:45Z-
dc.date.available2021-12-23T16:06:45Z-
dc.date.issued2007
dc.identifier.issn15257770
dc.identifier.urihttps://osnascholar.ub.uni-osnabrueck.de/handle/unios/7536-
dc.descriptionProceedings of the 17th International Roundtable of Nucleosides, Nucleotides, and Nucleic Acids, Bern, SWITZERLAND, MAR 07-SEP 07, 2006
dc.description.abstractOligonucleotides containing stretches of 2'-deoxycytidine residues were immobilized on 15 nm gold nanoparticles. Under acidic pH conditions a reversible supramolecular assembly is formed, induced by the formation of the tetrameric i-motif structure. The replacement of 2'-deoxycytidine by 5-propynyl-2'-deoxycytidine (dC*) leads to novel i-motif structures. Oligonucleotides incorporating multiple residues of dC* were immobilized on 15 nm gold nanoparticles and are able to aggregate into i-motif structures even at non-optimal pH values.
dc.language.isoen
dc.publisherTAYLOR & FRANCIS INC
dc.relation.ispartofNUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
dc.subject5-propynyl-2'-deoxycytidine
dc.subjectBiochemistry & Molecular Biology
dc.subjectDNA
dc.subjectgold nanoparticles
dc.subjecti-motif
dc.subjectself-assembly
dc.titlepH-dependent assembly of DNA-gold nanoparticles based on the i-motif
dc.typeconference paper
dc.identifier.doi10.1080/15257770701490803
dc.identifier.isiISI:000251875300046
dc.description.volume26
dc.description.issue6-7
dc.description.startpage755
dc.description.endpage759
dc.publisher.place325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
dcterms.isPartOf.abbreviationNucleosides Nucleotides Nucleic Acids
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