Nucleolipids as potential organogelators
Autor(en): | Rosemeyer, Helmut Stuerenberg, Eva-Maria Herdewijn, Piet |
Stichwörter: | Biochemistry & Molecular Biology; gelation properties; nucleolipid; organogelator | Erscheinungsdatum: | 2007 | Herausgeber: | TAYLOR & FRANCIS INC | Journal: | NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | Volumen: | 26 | Ausgabe: | 8-9 | Startseite: | 995 | Seitenende: | 999 | Zusammenfassung: | Four different series of nucleolipids or bola-nuclcolipids were synthesized or re-synthesized. Most of the compounds were studied with respect to their gelation properties toward either water or aromatic, hetero-aromatic, and aliphatic hydrocarbons. Bola-nucteolipids 6 and 7 do not gelate any solvent tested, neither as sole additive nor by adding up to 10 wt % of a 1:1 mixture. The nucleolipid 22 carrying the antiviral acyclovir as a head group proved to be a potent organogelator for aromatic hydrocarbons such as toluene, but not for hetarenes, aliphatic hydrocarbons or water. The mono-tailed nucleolipid 24 exhibits excellent organogelator Properties for both aromatic and aliphatic hydrocarbons. These were studied as a function of concentration and temperature. |
Beschreibung: | Proceedings of the 17th International Roundtable of Nucleosides, Nucleotides, and Nucleic Acids, Bern, SWITZERLAND, MAR 07-SEP 07, 2006 |
ISSN: | 15257770 | DOI: | 10.1080/15257770701508521 |
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