Atonic signs and symptoms: Assessing the `atopy score' concept
Autor(en): | Uter, W Schwanitz, HJ Pfahlberg, A Gefeller, O |
Stichwörter: | atopic dermatitis; atopy; DERMATITIS; Dermatology; diagnosis; DIAGNOSTIC-CRITERIA; epidemiology; TESTS; VALIDATION | Erscheinungsdatum: | 2001 | Herausgeber: | KARGER | Journal: | DERMATOLOGY | Volumen: | 202 | Ausgabe: | 1 | Startseite: | 4 | Seitenende: | 8 | Zusammenfassung: | Background: Score concepts have been suggested for the standardised diagnosis of atopic dermatitis, incorporating various anamnestic and clinical minor criteria of atopy, including the `Erlangen Score', developed in the hospital-based setting of a dermatitis clinic. Objective: To evaluate the properties of this score in the context of a population-based epidemiological study. Methods: The association between relevant atopic criteria and previous or current flexural eczema was evaluated in 2,352 hairdressing apprentices. Results: The association was not as strong as in the patient-based studies, comparing the respective odds ratios. Accordingly, the discriminating power of the Erlangen Score was poor, resulting in low sensitivity (55.7%) and specificity (73.8%) for, e.g., 8 points as cutpoint. Conclusion: While the score appears useful to summarise minor criteria, the individual relevance of its point values should not be overestimated in view of a low positive predictive value in a population (compared to a clinical) setting. Copyright (C) 2001 S. Karger AG, Basel. |
ISSN: | 10188665 | DOI: | 10.1159/000051576 |
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geprüft am 13.05.2024