Special issue on `Cytoskeletal proteins in health and neurodegenerative disease'

Autor(en): Brandt, Roland 
Gotz, Jurgen
Stichwörter: Neurosciences; Neurosciences & Neurology
Erscheinungsdatum: 2016
Herausgeber: PERGAMON-ELSEVIER SCIENCE LTD
Journal: BRAIN RESEARCH BULLETIN
Volumen: 126
Ausgabe: 3, SI
Startseite: 213
Seitenende: 216
Zusammenfassung: 
The cytoskeleton is the major intracellular structure that determines the morphology of neurons and maintains their structural integrity. It is therefore not surprising that a disturbance of cytoskeletal structure and functionunderlies many neurodegenerative diseases. This special issue brings together current information on the three majorneuronal cytoskeletal filament systems, microtubules, microfilaments and neurofilaments, and aims to provide a comprehensive overview of the role of the key components of these three systems under both physiological and pathological conditions. It therefore also addresses the role of microtubule-associated proteins (with a focus on tau) and motor proteins (with a focus on kinesin). (C) 2016 Published by Elsevier Inc.
ISSN: 03619230
DOI: 10.1016/j.brainresbull.2016.08.003

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