Nucleolipids: Natural occurrence, synthesis, molecular recognition, and supramolecular assemblies as potential precursors of life and bioorganic materials
Autor(en): | Rosemeyer, H | Stichwörter: | AGELAS-NAKAMURAI HOSHINO; AIR-WATER-INTERFACE; AMPHIPHILE OCTADECANOYL ESTER; BACTERIAL PEPTIDOGLYCAN SYNTHESIS; Biochemistry & Molecular Biology; CDP-DIACYLGLYCEROL ANALOGS; Chemistry; Chemistry, Multidisciplinary; CYTOSINE-ARABINOSIDE MOIETY; LANGMUIR-BLODGETT-FILMS; PRELIMINARY BIOLOGICAL EVALUATION; SHORT-CHAIN PHOSPHOLIPONUCLEOSIDES; TOXIC LIPONUCLEOTIDE ANALOGS | Erscheinungsdatum: | 2005 | Herausgeber: | VERLAG HELVETICA CHIMICA ACTA AG | Journal: | CHEMISTRY & BIODIVERSITY | Volumen: | 2 | Ausgabe: | 8 | Startseite: | 977 | Seitenende: | 1062 | Zusammenfassung: | Nucleolipids are hybrid molecules composed of a nucleobase, a nucleoside, a nucleotide or an oligonucleotide (either DNA or RNA), and a lipophilic moiety, which might be either simply a single- or double-chained alkyl (or alkenyl) moiety or a carbocyclic hydrocarbon such as cholesterol, a vitamin, or a bile acid. This review covers all aspects of nucleolipids, namely their natural occurrence, their synthesis, their molecular recognition, as well as aggregation behavior, either in aqueous or non-aqueous solution. Potential future aspects of nucleolipids in material sciences and for the elucidation of biochemical reactions in living cells are discussed. |
ISSN: | 16121872 | DOI: | 10.1002/cbdv.200590082 |
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geprüft am 21.05.2024