Nucleolipids: Natural occurrence, synthesis, molecular recognition, and supramolecular assemblies as potential precursors of life and bioorganic materials

Autor(en): Rosemeyer, H 
Stichwörter: AGELAS-NAKAMURAI HOSHINO; AIR-WATER-INTERFACE; AMPHIPHILE OCTADECANOYL ESTER; BACTERIAL PEPTIDOGLYCAN SYNTHESIS; Biochemistry & Molecular Biology; CDP-DIACYLGLYCEROL ANALOGS; Chemistry; Chemistry, Multidisciplinary; CYTOSINE-ARABINOSIDE MOIETY; LANGMUIR-BLODGETT-FILMS; PRELIMINARY BIOLOGICAL EVALUATION; SHORT-CHAIN PHOSPHOLIPONUCLEOSIDES; TOXIC LIPONUCLEOTIDE ANALOGS
Erscheinungsdatum: 2005
Herausgeber: VERLAG HELVETICA CHIMICA ACTA AG
Journal: CHEMISTRY & BIODIVERSITY
Volumen: 2
Ausgabe: 8
Startseite: 977
Seitenende: 1062
Zusammenfassung: 
Nucleolipids are hybrid molecules composed of a nucleobase, a nucleoside, a nucleotide or an oligonucleotide (either DNA or RNA), and a lipophilic moiety, which might be either simply a single- or double-chained alkyl (or alkenyl) moiety or a carbocyclic hydrocarbon such as cholesterol, a vitamin, or a bile acid. This review covers all aspects of nucleolipids, namely their natural occurrence, their synthesis, their molecular recognition, as well as aggregation behavior, either in aqueous or non-aqueous solution. Potential future aspects of nucleolipids in material sciences and for the elucidation of biochemical reactions in living cells are discussed.
ISSN: 16121872
DOI: 10.1002/cbdv.200590082

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