Eat in or Take out? Metabolism of Intracellular Salmonella enterica
DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Kehl, Alexander | |
dc.contributor.author | Noster, Janina | |
dc.contributor.author | Hensel, Michael | |
dc.date.accessioned | 2021-12-23T16:10:13Z | - |
dc.date.available | 2021-12-23T16:10:13Z | - |
dc.date.issued | 2020 | |
dc.identifier.issn | 0966842X | |
dc.identifier.uri | https://osnascholar.ub.uni-osnabrueck.de/handle/unios/9226 | - |
dc.description.abstract | Salmonella enterica is an important gastrointestinal and facultative intracellular pathogen. After invasion of host cells, it resides in a specialized, replication-permissive compartment, the Salmonella-containing vacuole (SCV). During maturation of the SCV, Salmonella remodels the host endosomal system to form a variety of membranous extensions from the SCV, one type designated Salmonella-induced filaments (SIFs). It was long unclear how Salmonella is able to sustain replication within the SCV, thought to be a nutrient-poor environment. Recent studies started to characterize the metabolic pathways used by intracellular Salmonella. Besides, new insights into the ultrastructure and biogenesis of SIFs and their essential role in nutrition were obtained lately. Here, we review the recent progress with focus on observations gained by various cellular models. | |
dc.description.sponsorship | DFGGerman Research Foundation (DFG)European Commission [HE 1964, SPP 1316, SPP 1580, SFB 944]; BMBFFederal Ministry of Education & Research (BMBF); Niedersachsisches Ministerium fur Wissenschaft und Kultur; Work in the authors' laboratory was supported by grants of the DFG (HE 1964, SPP 1316, SPP 1580, SFB 944), BMBF, and the Niedersachsisches Ministerium fur Wissenschaft und Kultur. We thank Viktoria Liss for the microscopy data used to generate Figure 1. | |
dc.language.iso | en | |
dc.publisher | ELSEVIER SCI LTD | |
dc.relation.ispartof | TRENDS IN MICROBIOLOGY | |
dc.subject | Biochemistry & Molecular Biology | |
dc.subject | COMPONENT | |
dc.subject | ENDOSOMAL SYSTEM | |
dc.subject | EXPRESSION | |
dc.subject | HOST-CELL | |
dc.subject | INFECTION | |
dc.subject | MACROPHAGES | |
dc.subject | MEMBRANE | |
dc.subject | Microbiology | |
dc.subject | STRESS | |
dc.subject | TRAFFICKING | |
dc.subject | TYPHIMURIUM | |
dc.title | Eat in or Take out? Metabolism of Intracellular Salmonella enterica | |
dc.type | review | |
dc.identifier.doi | 10.1016/j.tim.2020.03.005 | |
dc.identifier.isi | ISI:000548297600007 | |
dc.description.volume | 28 | |
dc.description.issue | 8 | |
dc.description.startpage | 644 | |
dc.description.endpage | 654 | |
dc.contributor.orcid | 0000-0002-8802-6605 | |
dc.contributor.orcid | 0000-0001-6604-6253 | |
dc.identifier.eissn | 18784380 | |
dc.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND | |
dcterms.isPartOf.abbreviation | Trends Microbiol. | |
crisitem.author.dept | FB 05 - Biologie/Chemie | - |
crisitem.author.deptid | fb05 | - |
crisitem.author.orcid | 0000-0001-6604-6253 | - |
crisitem.author.parentorg | Universität Osnabrück | - |
crisitem.author.netid | HeMi480 | - |
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geprüft am 01.06.2024