Auflistung: nach Autor Garcia, K. Christopher
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| Erscheinungsdatum | Titel | Autor(en) |
|---|---|---|
| 2015 | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency | Moraga, Ignacio; Richter, David; Wilmes, Stephan; Winkelmann, Hauke; Jude, Kevin; Thomas, Christoph; Suhoski, Megan M.; Engleman, Edgar G.; Piehler, Jacob ; Garcia, K. Christopher |
| 2017 | Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments | Richter, David; Moraga, Ignacio; Winkelmann, Hauke; Birkholz, Oliver; Wilmes, Stephan; Schulte, Markos; Kraich, Michael; Kenneweg, Hella; Beutel, Oliver; Selenschik, Philipp; Paterok, Dirk; Gavutis, Martynas; Schmidt, Thomas; Garcia, K. Christopher; Mueller, Thomas D.; Piehler, Jacob |
| 2022 | Live cell nanodot arrays uncover synergistic co-condensation of Wnt signalodroplets | Philippi, Michael; Richter, Christian; Kappen, Marie; Watrinet, Isabelle; Miao, Yi; Runge, Mercedes; Jorde, Lara; Korneev, Sergej; Holtmannspoetter, Michael; Kurre, Rainer ; Holthuis, Joost C. M.; Garcia, K. Christopher; Plueckthun, Andreas; Steinhart, Martin ; Piehler, Jacob ; You, Changjiang |
| 2020 | Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations | Wilmes, Stephan; Hafer, Maximillian; Vuorio, Joni; Tucker, Julie A.; Winkelmann, Hauke; Loechte, Sara; Stanly, Tess A.; Prieto, Katiuska D. Pulgar; Poojari, Chetan; Sharma, Vivek; Richter, Christian P.; Kurre, Rainer ; Hubbard, Stevan R.; Garcia, K. Christopher; Moraga, Ignacio; Vattulainen, Ilpo; Hitchcock, Ian S.; Piehler, Jacob |
| 2019 | New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2(V617F) Mutation | Wilmes, Stephan; Hafer, Maximillian; Stanly, Tess A.; Moraga, Ignacio; Vuorio, Joni; Poojari, Chetan; Sharma, Vivek; Lochte, Sara; Prieto, Katiuska Pulgar; Tucker, Julie A.; Hubbard, Stevan R.; Garcia, K. Christopher; Vattulainen, Ilpo; Hitchcock, Ian; Piehler, Jacob |
| 2020 | Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo | Miao, Yi; Ha, Andrew; de Lau, Wim; Yuki, Kanako; Santos, Antonio J. M.; You, Changjiang ; Geurts, Maarten H.; Puschhof, Jens; Pleguezuelos-Manzano, Cayetano; Peng, Weng Chuan; Senlice, Ramazan; Piani, Carol; Buikema, Jan W.; Gbenedio, Oghenekevwe M.; Vallon, Mario; Yuan, Jenny; de Haan, Sanne; Hemrika, Wieger; Rosch, Kathrin; Dang, Luke T.; Baker, David; Ott, Melanie; Depeille, Philippe; Wu, Sean M.; Drost, Jarno; Nusse, Roeland; Roose, Jeroen P.; Piehler, Jacob ; Boj, Sylvia F.; Janda, Claudia Y.; Clevers, Hans; Kuo, Calvin J.; Garcia, K. Christopher |
| 2022 | Organizing structural principles of the IL-17 ligand-receptor axis | Wilson, Steven C.; Caveney, Nathanael A.; Yen, Michelle; Pollmann, Christoph; Xiang, Xinyu; Jude, Kevin M.; Hafer, Maximillian; Tsutsumi, Naotaka; Piehler, Jacob ; Garcia, K. Christopher |
| 2016 | Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling | You, Changjiang ; Marquez-Lago, Tatiana T.; Richter, Christian Paolo; Wilmes, Stephan; Moraga, Ignacio; Garcia, K. Christopher; Leier, Andre; Piehler, Jacob |
| 2012 | Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation | Piehler, Jacob ; Thomas, Christoph; Garcia, K. Christopher; Schreiber, Gideon |
| 2011 | Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons | Thomas, Christoph; Moraga, Ignacio; Levin, Doron; Krutzik, Peter O.; Podoplelova, Yulia; Trejo, Angelica; Lee, Choongho; Yarden, Ganit; Vleck, Susan E.; Glenn, Jeffrey S.; Nolan, Garry P.; Piehler, Jacob ; Schreiber, Gideon; Garcia, K. Christopher |
| 2019 | Structure of the IFN gamma receptor complex guides design of biased agonists | Mendoza, Juan L.; Escalante, Nichole K.; Jude, Kevin M.; Bellon, Junel Sotolongo; Su, Leon; Horton, Tim M.; Tsutsumi, Naotaka; Berardinelli, Steven J.; Haltiwanger, Robert S.; Piehler, Jacob ; Engleman, Edgar G.; Garcia, K. Christopher |
| 2023 | Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis | Tsutsumi, Naotaka; Masoumi, Zahra; James, Sophie C.; Tucker, Julie A.; Winkelmann, Hauke; Grey, William; Picton, Lora K.; Moss, Lucie; Wilson, Steven C.; Caveney, Nathanael A.; Jude, Kevin M.; Gati, Cornelius; Piehler, Jacob ; Hitchcock, Ian S.; Garcia, K. Christopher |
| 2017 | Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling | Janda, Claudia Y.; Dang, Luke T.; You, Changjiang ; Chang, Junlei; de Lau, Wim; Zhong, Zhendong A.; Yan, Kelley S.; Marecic, Owen; Siepe, Dirk; Li, Xingnan; Moody, James D.; Williams, Bart O.; Clevers, Hans; Piehler, Jacob ; Baker, David; Kuo, Calvin J.; Garcia, K. Christopher |
| 2019 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis | Mohan, Kritika; Ueda, George; Kim, Ah Ram; Jude, Kevin M.; Fallas, Jorge A.; Guo, Yu; Hafer, Maximillian; Miao, Yi; Saxton, Robert A.; Piehler, Jacob ; Sankaran, Vijay G.; Baker, David; Garcia, K. Christopher |
| 2015 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands | Moraga, Ignacio; Wernig, Gerlinde; Wilmes, Stephan; Gryshkova, Vitalina; Richter, Christian P.; Hong, Wan-Jen; Sinha, Rahul; Guo, Feng; Fabionar, Hyna; Wehrman, Tom S.; Krutzik, Peter; Demharter, Samuel; Plo, Isabelle; Weissman, Irving L.; Minary, Peter; Majeti, Ravindra; Constantinescu, Stefan N.; Piehler, Jacob ; Garcia, K. Christopher |
| 2021 | Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors | Cui, Lu; Moraga, Ignacio; Lerbs, Tristan; Van Neste, Camille; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyros; Enge, Martin; Quake, Stephen; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde |
| 2020 | Tuning TPO-R signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia | Cui, Lu; Moraga, Ignacio; Lerbs, Tristan; Neste, Camille Van; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyridon; Enge, Martin; Quake, Stephen R.; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde |