Browsing by Author Garcia, K. Christopher
Showing results 16 to 24 of 24
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Issue Date | Title | Author(s) |
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2012 | Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation | Piehler, Jacob ; Thomas, Christoph; Garcia, K. Christopher; Schreiber, Gideon |
2011 | Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons | Thomas, Christoph; Moraga, Ignacio; Levin, Doron; Krutzik, Peter O.; Podoplelova, Yulia; Trejo, Angelica; Lee, Choongho; Yarden, Ganit; Vleck, Susan E.; Glenn, Jeffrey S.; Nolan, Garry P.; Piehler, Jacob ; Schreiber, Gideon; Garcia, K. Christopher |
2019 | Structure of the IFN gamma receptor complex guides design of biased agonists | Mendoza, Juan L.; Escalante, Nichole K.; Jude, Kevin M.; Bellon, Junel Sotolongo; Su, Leon; Horton, Tim M.; Tsutsumi, Naotaka; Berardinelli, Steven J.; Haltiwanger, Robert S.; Piehler, Jacob ; Engleman, Edgar G.; Garcia, K. Christopher |
2023 | Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis | Tsutsumi, Naotaka; Masoumi, Zahra; James, Sophie C.; Tucker, Julie A.; Winkelmann, Hauke; Grey, William; Picton, Lora K.; Moss, Lucie; Wilson, Steven C.; Caveney, Nathanael A.; Jude, Kevin M.; Gati, Cornelius; Piehler, Jacob ; Hitchcock, Ian S.; Garcia, K. Christopher |
2017 | Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling | Janda, Claudia Y.; Dang, Luke T.; You, Changjiang ; Chang, Junlei; de Lau, Wim; Zhong, Zhendong A.; Yan, Kelley S.; Marecic, Owen; Siepe, Dirk; Li, Xingnan; Moody, James D.; Williams, Bart O.; Clevers, Hans; Piehler, Jacob ; Baker, David; Kuo, Calvin J.; Garcia, K. Christopher |
2019 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis | Mohan, Kritika; Ueda, George; Kim, Ah Ram; Jude, Kevin M.; Fallas, Jorge A.; Guo, Yu; Hafer, Maximillian; Miao, Yi; Saxton, Robert A.; Piehler, Jacob ; Sankaran, Vijay G.; Baker, David; Garcia, K. Christopher |
2015 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands | Moraga, Ignacio; Wernig, Gerlinde; Wilmes, Stephan; Gryshkova, Vitalina; Richter, Christian P.; Hong, Wan-Jen; Sinha, Rahul; Guo, Feng; Fabionar, Hyna; Wehrman, Tom S.; Krutzik, Peter; Demharter, Samuel; Plo, Isabelle; Weissman, Irving L.; Minary, Peter; Majeti, Ravindra; Constantinescu, Stefan N.; Piehler, Jacob ; Garcia, K. Christopher |
2021 | Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors | Cui, Lu; Moraga, Ignacio; Lerbs, Tristan; Van Neste, Camille; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyros; Enge, Martin; Quake, Stephen; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde |
2020 | Tuning TPO-R signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia | Cui, Lu; Moraga, Ignacio; Lerbs, Tristan; Neste, Camille Van; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyridon; Enge, Martin; Quake, Stephen R.; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde |