Piehler, Jacob
Full Name
Piehler, Jacob
Variants
Piehler, J
Piehler, Jacob
Piehler, Jacob
Main Affiliation
FIS NetID
ORCID
Country
Germany
Lädt ...
2
0
20
0
false
Lädt ...
3
0
20
0
false
Erscheinungsdatum
Typ
1-20 von 21
| Erscheinungsdatum | Titel | Autor(en) | |
|---|---|---|---|
| 1 | 2011 | Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons | Thomas, Christoph; Moraga, Ignacio; Levin, Doron; Krutzik, Peter O.; Podoplelova, Yulia; Trejo, Angelica; Lee, Choongho; Yarden, Ganit; Vleck, Susan E.; Glenn, Jeffrey S.; Nolan, Garry P.; Piehler, Jacob ; Schreiber, Gideon; Garcia, K. Christopher |
| 2 | 2015 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands | Moraga, Ignacio; Wernig, Gerlinde; Wilmes, Stephan; Gryshkova, Vitalina; Richter, Christian P.; Hong, Wan-Jen; Sinha, Rahul; Guo, Feng; Fabionar, Hyna; Wehrman, Tom S.; Krutzik, Peter; Demharter, Samuel; Plo, Isabelle; Weissman, Irving L.; Minary, Peter; Majeti, Ravindra; Constantinescu, Stefan N.; Piehler, Jacob ; Garcia, K. Christopher |
| 3 | 2015 | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency | Moraga, Ignacio; Richter, David; Wilmes, Stephan; Winkelmann, Hauke; Jude, Kevin; Thomas, Christoph; Suhoski, Megan M.; Engleman, Edgar G.; Piehler, Jacob ; Garcia, K. Christopher |
| 4 | 2016 | Discovery of the First Pathogenic Human EPO Mutation Provides Mechanistic Insight into Cytokine Signaling | Kim, Ah Ram; Ulirsch, Jacob C.; Wilmes, Stephan; Unal, Ekrem; Moraga, Ignacio; Karakukcu, Musa; Yuan, Daniel; Kazerounian, Shideh; Gupta, Namrata; Gabriel, Stacey B.; Lander, Eric S.; Patiroglu, Turkan; Ozcan, Alper; Ozdemir, Mehmet; Garcia, Christopher; Piehler, Jacob ; Gazda, Hanna; Klein, Daryl; Sankaran, Vijay G. |
| 5 | 2016 | Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling | You, Changjiang ; Marquez-Lago, Tatiana T.; Richter, Christian Paolo; Wilmes, Stephan; Moraga, Ignacio; Garcia, K. Christopher; Leier, Andre; Piehler, Jacob |
| 6 | 2017 | Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling | Ho, Chia Chi M.; Chhabra, Akanksha; Starkl, Philipp; Schnorr, Peter-John; Wilmes, Stephan; Moraga, Ignacio; Kwon, Hye-Sook; Gaudenzio, Nicolas; Sibilano, Riccardo; Wehrman, Tom S.; Gakovic, Milica; Sockolosky, Jonathan T.; Tiffany, Matthew R.; Ring, Aaron M.; Piehler, Jacob ; Weissman, Irving L.; Galli, Stephen J.; Shizuru, Judith A.; Garcia, K. Christopher |
| 7 | 2017 | Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments | Richter, David; Moraga, Ignacio; Winkelmann, Hauke; Birkholz, Oliver; Wilmes, Stephan; Schulte, Markos; Kraich, Michael; Kenneweg, Hella; Beutel, Oliver; Selenschik, Philipp; Paterok, Dirk; Gavutis, Martynas; Schmidt, Thomas; Garcia, K. Christopher; Mueller, Thomas D.; Piehler, Jacob |
| 8 | 2017 | Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation | Kim, Ah Ram; Ulirsch, Jacob C.; Wilmes, Stephan; Unal, Ekrem; Moraga, Ignacio; Karakukcu, Musa; Yuan, Daniel; Kazerounian, Shideh; Abdulhay, Nour J.; King, David S.; Gupta, Namrata; Gabriel, Stacey B.; Lander, Eric S.; Patiroglu, Turkan; Ozcan, Alper; Ozdemir, Mehmet Akif; Garcia, K. Christopher; Piehler, Jacob ; Gazda, Hanna T.; Klein, Daryl E.; Sankaran, Vijay G. |
| 9 | 2019 | New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2(V617F) Mutation | Wilmes, Stephan; Hafer, Maximillian; Stanly, Tess A.; Moraga, Ignacio; Vuorio, Joni; Poojari, Chetan; Sharma, Vivek; Lochte, Sara; Prieto, Katiuska Pulgar; Tucker, Julie A.; Hubbard, Stevan R.; Garcia, K. Christopher; Vattulainen, Ilpo; Hitchcock, Ian; Piehler, Jacob |
| 10 | 2019 | Kinetics of cytokine receptor trafficking determine signaling and functional selectivity | Martinez-Fabregas, Jonathan; Wilmes, Stephan; Wang, Luopin; Hafer, Maximillian; Pohler, Elizabeth; Lokau, Juliane; Garbers, Christoph; Cozzani, Adeline; Fyfe, Paul K.; Piehler, Jacob ; Kazemian, Majid; Mitra, Suman; Moraga, Ignacio |
| 11 | 2019 | Kinetics of cytokine receptor trafficking determine signaling and functional selectivity | Martinez-Fabregas, Jonathan; Wilmes, Stephan; Wang, Luopin; Hafer, Maximillian; Pohler, Elizabeth; Lokau, Juliane; Garbers, Christoph; Cozzani, Adeline; Piehler, Jacob ; Kazemian, Majid; Mitra, Suman; Moraga, Ignacio |
| 12 | 2019 | Author response: Kinetics of cytokine receptor trafficking determine signaling and functional selectivity | Martinez-Fabregas, Jonathan; Wilmes, Stephan; Wang, Luopin; Hafer, Maximillian; Pohler, Elizabeth; Lokau, Juliane; Garbers, Christoph; Cozzani, Adeline; Fyfe, Paul K.; Piehler, Jacob ; Kazemian, Majid; Mitra, Suman; Moraga, Ignacio |
| 13 | 2020 | Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses | Gorby, Claire; Bellon, Junel Sotolongo; Wilmes, Stephan; Warda, Walid; Pohler, Elizabeth; Fyfe, Paul K.; Cozzani, Adeline; Ferrand, Christophe; Walter, Mark R.; Mitra, Suman; Piehler, Jacob ; Moraga, Ignacio |
| 14 | 2020 | Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations | Wilmes, Stephan; Hafer, Maximillian; Vuorio, Joni; Tucker, Julie A.; Winkelmann, Hauke; Loechte, Sara; Stanly, Tess A.; Prieto, Katiuska D. Pulgar; Poojari, Chetan; Sharma, Vivek; Richter, Christian P.; Kurre, Rainer ; Hubbard, Stevan R.; Garcia, K. Christopher; Moraga, Ignacio; Vattulainen, Ilpo; Hitchcock, Ian S.; Piehler, Jacob |
| 15 | 2020 | Engineered IL-10 variants elicit potent immuno-modulatory activities at therapeutic low ligand doses | Gorby, Claire; J, Sotolongo Bellón; Wilmes, S.; Warda, Walid; Pohler, Elizabeth; Fyfe, Paul K.; Cozzani, Adeline; Ferrand, Christophe; Walter, M. Todd; Mitra, S.; Piehler, Jacob ; Moraga, Ignacio |
| 16 | 2020 | Tuning TPO-R signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia | Cui, Lu; Moraga, Ignacio; Lerbs, Tristan; Neste, Camille Van; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyridon; Enge, Martin; Quake, Stephen R.; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde |
| 17 | 2021 | Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses | Wilmes, Stephan; Jeffrey, Polly-Anne; Martinez-Fabregas, Jonathan; Hafer, Maximillian; Fyfe, Paul K.; Pohler, Elizabeth; Gaggero, Silvia; Lopez-Garcia, Martin; Lythe, Grant; Taylor, Charles; Guerrier, Thomas; Launay, David; Mitra, Suman; Piehler, Jacob ; Molina-Paris, Carmen; Moraga, Ignacio |
| 18 | 2021 | Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors | Cui, Lu; Moraga, Ignacio; Lerbs, Tristan; Van Neste, Camille; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyros; Enge, Martin; Quake, Stephen; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde |
| 19 | 2021 | Author response: Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses | Wilmes, Stephan; Jeffrey, Polly-Anne; Martinez-Fabregas, Jonathan; Hafer, Maximillian; Fyfe, Paul K.; Pohler, Elizabeth; Gaggero, Silvia; López-García, Martín; Lythe, Grant; Taylor, Charles; Guerrier, T.; Launay, David; Mitra, Suman; Piehler, Jacob ; Molina-París, Carmen; Moraga, Ignacio |
| 20 | 2021 | Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses in autoimmune disorders | Wilmes, Stephan; Jeffrey, Polly-Anne; Martinez-Fabregas, Jonathan; Hafer, Maximillian; Fyfe, Paul K.; Pohler, Elizabeth; Gaggero, Silvia; López-García, Martín; Lythe, Grant; Guerrier, T.; Launay, David; Suman, Mitra; Piehler, Jacob ; Molina-París, Carmen; Moraga, Ignacio |