Magnetic control of cellular processes using biofunctional nanoparticles
Autor(en): | Monzel, Cornelia Vicario, Chiara Piehler, Jacob Coppey, Mathieu Dahan, Maxime |
Stichwörter: | BEHAVIOR; CANCER-CELLS; CHANNELS; Chemistry; Chemistry, Multidisciplinary; DRUG-DELIVERY; IRON-OXIDE NANOPARTICLES; OPTOGENETIC CONTROL; OSTEOGENIC DIFFERENTIATION; RELEASE; SPATIOTEMPORAL CONTROL; SURFACE | Erscheinungsdatum: | 2017 | Herausgeber: | ROYAL SOC CHEMISTRY | Journal: | CHEMICAL SCIENCE | Volumen: | 8 | Ausgabe: | 11 | Startseite: | 7330 | Seitenende: | 7338 | Zusammenfassung: | Remote control of cellular functions is a key challenge in biomedical research. Only a few tools are currently capable of manipulating cellular events at distance, at spatial and temporal scales matching their naturally active range. A promising approach, often referred to as `magnetogenetics', is based on the use of magnetic fields, in conjunction with targeted biofunctional magnetic nanoparticles. By triggering molecular stimuli via mechanical, thermal or biochemical perturbations, magnetic actuation constitutes a highly versatile tool with numerous applications in fundamental research as well as exciting prospects in nano-and regenerative medicine. Here, we highlight recent studies, comment on the advancement of magnetic manipulation, and discuss remaining challenges. |
ISSN: | 20416520 | DOI: | 10.1039/c7sc01462g |
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geprüft am 05.05.2024